ZXDC and JTB

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		ZXDC	JTB
Description		ZXD family zinc finger C	jumping translocation breakpoint
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Mitochondrion Centrosome Spindle Cytoskeleton Plasma Membrane Membrane Midbody
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Zinc Ion Binding LRR Domain Binding Metal Ion Binding C2H2 Zinc Finger Domain Binding	Protein Kinase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription	Mitotic Cell Cycle Mitotic Cytokinesis Apoptotic Process Apoptotic Mitochondrial Changes Regulation Of Cell Population Proliferation Positive Regulation Of Protein Kinase Activity Cell Division
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Pursuit maintenance gain ( 29064472)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: APP ATXN1 CBR4 CIITA JTB MEPE MTDH NR1H2 NR1H3 POGZ RORA SH3GL2 SMN1 SUOX TK1 WDR5 ZMYND19	4 interacting genes: APP ELOC LIG3 ZXDC
Entrez ID		79364	10899
HPRD ID		14420	05240
Ensembl ID		ENSG00000070476	ENSG00000143543
Uniprot IDs		Q2QGD7	O76095
PDB IDs			2KJX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Regulation Of Small Molecule Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of DNA-templated Transcription Nuclear Receptor Activity Negative Regulation Of Type II Interferon-mediated Signaling Pathway Negative Regulation Of Pinocytosis Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cholesterol Storage Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Negative Regulation Of Macrophage Derived Foam Cell Differentiation Protein Tetramerization Regulation Of Response To Endoplasmic Reticulum Stress Sterol Homeostasis Cholesterol Homeostasis Phosphatidylcholine Acyl-chain Remodeling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Regulation Of Triglyceride Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Endocytosis Negative Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cholesterol Efflux Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Metabolic Process Lipid Homeostasis Positive Regulation Of Cholesterol Transport Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Inflammatory Response Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Biosynthetic Process Acylglycerol Homeostasis Negative Regulation Of Inflammatory Response Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Amyloid-beta Complex	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Mitochondrial DNA Replication Negative Regulation Of Mitochondrial DNA Replication DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Ligase III-XRCC1 Complex DNA Ligase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Mitochondrial DNA Metabolic Process Target-directed MiRNA Degradation Elongin Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway LRR Domain Binding Axon Choice Point Recognition Mitochondrial DNA Repair Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Double-strand Break Repair Via Alternative Nonhomologous End Joining Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Blood Circulation
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