ZXDC and POGZ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZXDC	POGZ
Description		ZXD family zinc finger C	pogo transposable element derived with ZNF domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane Ciliary Basal Body
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Zinc Ion Binding LRR Domain Binding Metal Ion Binding C2H2 Zinc Finger Domain Binding	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Mitotic Sister Chromatid Cohesion Positive Regulation Of Transcription By RNA Polymerase II Cell Division Kinetochore Assembly
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Pursuit maintenance gain ( 29064472)	Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pulse pressure ( 30578418)
Interacting Genes		17 interacting genes: APP ATXN1 CBR4 CIITA JTB MEPE MTDH NR1H2 NR1H3 POGZ RORA SH3GL2 SMN1 SUOX TK1 WDR5 ZMYND19	87 interacting genes: A1CF ACTMAP AGR2 ANKRD10 AOC1 APP ATXN1 BANP BOLL C10orf55 CCDC136 CDK6 CERCAM CREB1 CRX DAB1 DAZAP2 DMXL1 DTX2 EID2B EIF3F EYA2 FAM168B FCSK FHL2 FNDC3B FOSB GABPB1 GMEB2 H3-4 HGS HIVEP1 HSF2BP HSPB2 HSPB2-C11orf52 HYI JMJD7 KLHDC7B KLHL26 KRTAP3-2 KRTAP6-2 KRTAP8-1 LITAF MBLAC1 MYO1B NFYA NFYC NHLRC4 NICN1 NRF1 ODAM PFDN5 PIDD1 PLEKHB2 PLIN2 POU2AF1 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RBFOX1 RBPMS RSPH1 SP1 SP3 SP4 SPATA12 SPRYD7 STH SUMO2 TBX19 TCIRG1 TMBIM4 TSC1 UFSP1 VAV2 VEZF1 VGLL3 ZBTB24 ZNF143 ZNF410 ZNF710 ZNF76 ZXDC
Entrez ID		79364	23126
HPRD ID		14420	11445
Ensembl ID		ENSG00000070476	ENSG00000143442
Uniprot IDs		Q2QGD7	A0A8V8TQ67 Q7Z3K3
PDB IDs			2E72 2N3A 6EMP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Regulation Of Small Molecule Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of DNA-templated Transcription Nuclear Receptor Activity Negative Regulation Of Type II Interferon-mediated Signaling Pathway Negative Regulation Of Pinocytosis Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cholesterol Storage Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Negative Regulation Of Macrophage Derived Foam Cell Differentiation Protein Tetramerization Regulation Of Response To Endoplasmic Reticulum Stress Sterol Homeostasis Cholesterol Homeostasis Phosphatidylcholine Acyl-chain Remodeling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Regulation Of Triglyceride Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Endocytosis Negative Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cholesterol Efflux Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Metabolic Process Lipid Homeostasis Positive Regulation Of Cholesterol Transport Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Inflammatory Response Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Biosynthetic Process Acylglycerol Homeostasis Negative Regulation Of Inflammatory Response Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Amyloid-beta Complex	Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA Binding Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA-binding Transcription Factor Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Transcription Regulator Complex Protein-DNA Complex DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process CCAAT-binding Factor Complex Identical Protein Binding Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Sequence-specific Double-stranded DNA Binding Adult Locomotory Behavior
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