APLP1 and RBM48

Number of citations of the paper that reports this interaction (PMID 15383276)
99

Data Source:
BioGRID (two hybrid)

		APLP1	RBM48
Gene Name		amyloid beta (A4) precursor-like protein 1	RNA binding motif protein 48
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	RNA Binding
	Biological Process	MRNA Polyadenylation Regulation Of Translation Endocytosis Apoptotic Process Cell Adhesion Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Nervous System Development Organ Morphogenesis Extracellular Matrix Organization Negative Regulation Of CAMP Biosynthetic Process Forebrain Development Cellular Response To Norepinephrine Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: ANXA7 APBB1 APBB3 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	50 interactors: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24
Entrez ID		333	84060
HPRD ID		00102	13173
Ensembl ID		ENSG00000105290	ENSG00000127993
Uniprot IDs		F5GZ08 P51693	B4DGJ6 B7Z2K5 Q5RL73
PDB IDs		3PMR 3Q7G 3Q7L 3QMK
Enriched GO Terms of Interacting Partners?		Developmental Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Anatomical Structure Development Positive Regulation Of Protein Metabolic Process System Development Positive Regulation Of Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Multicellular Organismal Development Regulation Of Phosphorylation Response To Organic Substance Regulation Of Gene Expression Response To Copper Ion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Process Regulation Of Cell Proliferation Positive Regulation Of Protein Phosphorylation Cellular Aromatic Compound Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cell Death Regulation Of Kinase Activity Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Copper Ion Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Negative Regulation Of Growth Response To Growth Factor Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Growth Positive Regulation Of Cell Death Positive Regulation Of Phosphorylation Heterocycle Metabolic Process Response To Organic Cyclic Compound Digestive Tract Development Negative Regulation Of Cellular Metabolic Process Cell Cycle Arrest RNA Metabolic Process Response To Inorganic Substance Regulation Of Cell Cycle Digestive System Development Negative Regulation Of Cell Growth G1/S Transition Of Mitotic Cell Cycle	Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Developmental Process Response To Stimulus Central Nervous System Development MRNA Polyadenylation Nucleoside Metabolic Process Negative Regulation Of Transferase Activity RNA Polyadenylation Regulation Of Cell Cycle Negative Regulation Of Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Apoptotic Process Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Kinase Activity Regulation Of Cell Cycle Phase Transition Response To Stress Negative Regulation Of Catalytic Activity Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death MRNA Processing Multicellular Organismal Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Regulation Of Cellular Protein Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Mitotic Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Protein Phosphorylation Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest
Tagcloud ?		abundance allocated analyzing aplp2 app apparatus appsalpha attached compartments corresponds endosomal golgi homozygous immunopurification impacts knockout ko organellar pool presynaptic residing sv2 sv2a synaptic synaptogamin synaptophysin synaptotagmin vesicle zone
Tagcloud (Difference) ?		abundance allocated analyzing aplp2 app apparatus appsalpha attached compartments corresponds endosomal golgi homozygous immunopurification impacts knockout ko organellar pool presynaptic residing sv2 sv2a synaptic synaptogamin synaptophysin synaptotagmin vesicle zone
Tagcloud (Intersection) ?