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APLP1 and GDF9
Number of citations of the paper that reports this interaction (PubMedID
15383276
)
0
Data Source:
BioGRID
(two hybrid)
APLP1
GDF9
Description
amyloid beta precursor like protein 1
growth differentiation factor 9
Image
No pdb structure
GO Annotations
Cellular Component
Basement Membrane
Nucleoplasm
Cytoplasm
Golgi Apparatus
Plasma Membrane
Membrane
Perinuclear Region Of Cytoplasm
Extracellular Region
Extracellular Space
Cytoplasm
Molecular Function
Protein Binding
Heparin Binding
Alpha-2A Adrenergic Receptor Binding
Alpha-2B Adrenergic Receptor Binding
Alpha-2C Adrenergic Receptor Binding
Identical Protein Binding
Metal Ion Binding
Transition Metal Ion Binding
Cytokine Activity
Growth Factor Activity
Biological Process
Regulation Of Translation
Endocytosis
Apoptotic Process
Cell Adhesion
Nervous System Development
Axonogenesis
Central Nervous System Development
Animal Organ Morphogenesis
Extracellular Matrix Organization
Forebrain Development
Animal Organ Development
Cellular Response To Norepinephrine Stimulus
Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cytosolic MRNA Polyadenylation
Oocyte Growth
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Growth
Regulation Of Progesterone Secretion
Pathways
Drugs
Zinc
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Severe influenza A (H1N1) infection (
26379185
)
Asthma (
31619474
)
Interacting Genes
42 interacting genes:
ANXA7
APBB1
CDK4
CDKN1A
CDKN2C
CRCT1
CSNK2B
DAB1
DAB2
EEF1A1
EIF2S2
GDF9
GSTM4
HAP1
HLA-DQA1
HSPE1
ING5
KAT5
LRIF1
MPHOSPH6
NACA
PCDHA4
PHF10
PIN1
PNP
PRNP
RAP1B
RBM48
RCC1
SAT1
SETDB1
SMN1
SNCA
STX5
TCF21
TK1
TMSB4X
TOE1
TSC22D1
UTP14A
VIM
ZNF24
45 interacting genes:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CDKN1A
CDKN2C
CRELD1
CRIPTO
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TK1
TRIB3
WASHC3
Entrez ID
333
2661
HPRD ID
00102
03560
Ensembl ID
ENSG00000105290
ENSG00000164404
Uniprot IDs
P51693
B4DXG3
O60383
PDB IDs
3PMR
3Q7G
3Q7L
3QMK
4RD9
4RDA
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Component Organization
Inclusion Body
Cytoplasm
Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Amyloid-beta Formation
Regulation Of Amide Metabolic Process
Molecular Adaptor Activity
Regulation Of Cell Cycle G1/S Phase Transition
Nucleus
Chromatin Binding
Cytosol
Protein Sequestering Activity
Regulation Of Chaperone-mediated Autophagy
Regulation Of Amyloid-beta Formation
Negative Regulation Of Growth
Cuprous Ion Binding
Regulation Of Protein Catabolic Process
Regulation Of Amyloid Precursor Protein Catabolic Process
Response To Phorbol 13-acetate 12-myristate
Regulation Of Cell Population Proliferation
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Regulation Of Interleukin-2 Production
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Cell Cycle Phase Transition
Regulation Of SMAD Protein Signal Transduction
Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Cell Growth
Identical Protein Binding
Regulation Of Cell Development
Negative Regulation Of Androgen Receptor Signaling Pathway
Regulation Of Cell Activation
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Projection Organization
Cell Cycle G1/S Phase Transition
BMP Receptor Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Cellular Response To BMP Stimulus
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Ossification
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Activin Receptor Activity, Type II
BMP Binding
Positive Regulation Of Osteoblast Differentiation
Tricuspid Valve Morphogenesis
Activin Receptor Signaling Pathway
Regulation Of Bone Mineralization
BMP Signaling Pathway
Transforming Growth Factor Beta Receptor Activity, Type I
Negative Regulation Of Chondrocyte Proliferation
Regionalization
Endochondral Bone Morphogenesis
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Developmental Process
Positive Regulation Of SMAD Protein Signal Transduction
HFE-transferrin Receptor Complex
Mitral Valve Morphogenesis
RNA Splicing, Via Transesterification Reactions
Regulation Of Ossification
Pharyngeal Arch Artery Morphogenesis
Osteoblast Differentiation
Mesenchyme Development
Endocardial Cushion Development
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Positive Regulation Of Programmed Cell Death
Pattern Specification Process
Regulation Of Osteoblast Differentiation
Dorsal/ventral Pattern Formation
Cellular Response To Growth Factor Stimulus
Regulation Of SMAD Protein Signal Transduction
Cellular Developmental Process
Cell Differentiation
SMN-Sm Protein Complex
FAR/SIN/STRIPAK Complex
Anterior/posterior Pattern Specification
Kinase Activity
Precatalytic Spliceosome
Atrioventricular Valve Morphogenesis
Epithelial Cell Proliferation
Protein Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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