TWSG1

Description		twisted gastrulation BMP signaling modulator 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Heparin Binding Transforming Growth Factor Beta Binding
	Biological Process	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Chondrocyte Differentiation Salivary Gland Morphogenesis Tissue Development Hemopoiesis BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Interacting Genes		10 interacting genes: BMP1 BMP4 CHRD FAM209A FNDC9 GJA8 GPRC5D LRRC4C SGTA TNS2
Entrez ID		57045
HPRD ID		05443
Ensembl ID		ENSG00000128791
Uniprot IDs		Q9GZX9
PDB IDs		8BWA 8BWD 8BWI 8BWL 8BWM 8BWN
Enriched GO Terms of Interacting Partners?		Dorsal/ventral Pattern Formation Positive Regulation Of Cartilage Development Skeletal System Development Regionalization Negative Regulation Of Metanephric Comma-shaped Body Morphogenesis Bud Dilation Involved In Lung Branching Apoptotic Process Involved In Endocardial Cushion Morphogenesis Negative Regulation Of Mesenchymal Cell Proliferation Involved In Ureter Development Intermediate Mesodermal Cell Differentiation Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Metanephric S-shaped Body Morphogenesis Positive Regulation Of Cardiac Muscle Fiber Development Negative Regulation Of Glomerulus Development Negative Regulation Of BMP Signaling Pathway Regulation Of Cartilage Development Positive Regulation Of Primary MiRNA Processing Tendon Cell Differentiation Negative Regulation Of Branching Involved In Ureteric Bud Morphogenesis Camera-type Eye Development BMP Signaling Pathway Positive Regulation Of Branching Involved In Lung Morphogenesis TRC Complex Pattern Specification Process Growth Factor Activity Cartilage Development Ossification Apoptotic Process Involved In Heart Morphogenesis Regulation Of Osteoblast Differentiation Positive Regulation Of MiRNA Processing Negative Regulation Of Glomerular Mesangial Cell Proliferation Nephric Duct Formation Bronchus Development Positive Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Deltoid Tuberosity Development Epithelial Cell Proliferation Involved In Lung Morphogenesis Cardiac Jelly Development Eye Development Negative Regulation Of Immature T Cell Proliferation Prostate Gland Morphogenesis Epithelial-mesenchymal Cell Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Branching Involved In Lung Morphogenesis Telencephalon Regionalization Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Branching Involved In Prostate Gland Morphogenesis Glomerular Capillary Formation Pericyte Cell Differentiation Specification Of Animal Organ Position Regulation Of BMP Signaling Pathway Trachea Development
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