TWSG1

Gene Name		twisted gastrulation BMP signaling modulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome
	Molecular Function
	Biological Process	Ossification Mesoderm Formation Salivary Gland Morphogenesis Hemopoiesis Cell Differentiation BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-protein Interactions		4 interactors: BMP1 BMP4 CHRD SGTA
Entrez ID		57045
HPRD ID		05443
Ensembl ID		ENSG00000128791
Uniprot IDs		Q9GZX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Ossification Positive Regulation Of Cartilage Development Regulation Of Mesenchymal Cell Proliferation Skeletal System Development BMP Signaling Pathway Regulation Of BMP Signaling Pathway Mesoderm Formation Regulation Of Cartilage Development Mesoderm Morphogenesis Regulation Of Stem Cell Proliferation Dorsal/ventral Pattern Formation Negative Regulation Of Metanephric S-shaped Body Morphogenesis Negative Regulation Of Metanephric Comma-shaped Body Morphogenesis BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Mesenchymal Cell Proliferation Involved In Ureter Development Ureter Epithelial Cell Differentiation Negative Regulation Of Mesenchymal Cell Proliferation Involved In Ureter Development Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Pulmonary Artery Endothelial Tube Morphogenesis BMP Signaling Pathway Involved In Renal System Segmentation BMP Signaling Pathway Involved In Ureter Morphogenesis Negative Regulation Of Branch Elongation Involved In Ureteric Bud Branching By BMP Signaling Pathway Specification Of Ureteric Bud Anterior/posterior Symmetry By BMP Signaling Pathway Positive Regulation Of Cardiac Muscle Fiber Development Bud Dilation Involved In Lung Branching Epithelial Cell Proliferation Involved In Lung Morphogenesis BMP Signaling Pathway Involved In Nephric Duct Formation Intermediate Mesodermal Cell Differentiation Regulation Of Osteoblast Differentiation Formation Of Primary Germ Layer Osteoblast Differentiation Mesoderm Development Intermediate Mesoderm Development Gastrulation Neural Tube Development Cartilage Development Regulation Of Ossification Negative Regulation Of Glomerular Mesangial Cell Proliferation Ureter Urothelium Development Mesenchymal Cell Proliferation Involved In Ureteric Bud Development Cloacal Septation Negative Regulation Of Glomerulus Development Mesodermal Cell Fate Determination BMP Signaling Pathway Involved In Heart Induction Deltoid Tuberosity Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Ureter Morphogenesis Ureter Smooth Muscle Cell Differentiation Regulation Of Branch Elongation Involved In Ureteric Bud Branching
Tagcloud ?		acted anomaly bmp bmp2 concert dams e11 e9 embryonal expressivity forebrain gastrulation gavage geometric holoprosencephaly hpe manifested microct midface midline morphometric narrowing ntd overt p19 penetrance predisposing teratogenesis twisted