MAGEB4 and TRAK1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		MAGEB4	TRAK1
Name		MAGE family member B4	trafficking kinesin protein 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Mitochondrion Endosome Early Endosome Cytosol Cell Cortex Membrane Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axonal Growth Cone Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Myosin Binding TPR Domain Binding GABA Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Axonal Transport Of Mitochondrion Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Dendrite Morphogenesis Positive Regulation Of Axonogenesis
Pathways		None	Signaling by BRAF and RAF1 fusions RHOT2 GTPase cycle RHOT1 GTPase cycle
GWAS		No GWAS studies recorded	Body mass index ( 28552196 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) PR interval ( 32439900 ) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962 ) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962 ) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738 )
Interacting Genes		41 interacting genes: AARD ACOT11 ARID3A BLOC1S1 CCDC136 CCDC14 CIMIP2B DVL3 EEF1AKMT3 FAM136A FERD3L FLOT2 FTSJ3 GOLGA6L2 GPATCH2 H2AP HGS IHO1 KANK2 KRT38 LZTS2 MAGEA8 MED21 MESD NEUROD4 PFDN6 PICK1 PJA1 ROCK1 RUNDC3A SH2D1B THOC1 TNR TRAK1 UQCRB USHBP1 USP25 WDR62 YWHAE ZNF341 ZRANB1	17 interacting genes: BLOC1S6 BYSL CDC5L CDK6 ENKD1 ESS2 HGS MAGEB4 OGT POLR2A PRPF6 PTBP1 SKIL SNW1 TRAF3IP1 UTP6 ZNF232
Entrez ID		4115	22906
HPRD ID		02150	09732
Ensembl ID		ENSG00000120289	ENSG00000182606
Uniprot IDs		O15481	A0A087X0N0 A0A0D9SFL5 B7Z218 B7ZAE5 C9JC32 Q9UPV9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Catalytic Step 2 Spliceosome RNA Processing RNA Metabolic Process Spliceosomal Complex RNA Splicing MRNA Metabolic Process Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Prp19 Complex Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) SnoRNA Binding Blastocyst Formation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Dentate Gyrus Development Regulation Of Cellular Response To Growth Factor Stimulus U2-type Catalytic Step 2 Spliceosome Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Organelle Assembly Maturation Of SSU-rRNA Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Ciliary Base Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin D2-CDK6 Complex Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle SMAD Binding Nucleus Regulation Of Macromolecule Metabolic Process Protein Domain Specific Binding Protein Localization To Lysosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Transcription By RNA Polymerase II Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding