MAGEB4 and ARID3A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEB4	ARID3A
Description		MAGE family member B4	AT-rich interaction domain 3A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Raft
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways			TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Drugs
Diseases
GWAS			High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Primary biliary cholangitis ( 28425483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio ( 20548946)
Interacting Genes		41 interacting genes: AARD ACOT11 ARID3A BLOC1S1 CCDC136 CCDC14 CIMIP2B DVL3 EEF1AKMT3 FAM136A FERD3L FLOT2 FTSJ3 GOLGA6L2 GPATCH2 H2AP HGS IHO1 KANK2 KRT38 LZTS2 MAGEA8 MED21 MESD NEUROD4 PFDN6 PICK1 PJA1 ROCK1 RUNDC3A SH2D1B THOC1 TNR TRAK1 UQCRB USHBP1 USP25 WDR62 YWHAE ZNF341 ZRANB1	21 interacting genes: ANKRD11 APP BTK DSP E2F1 E2F2 E2F4 KRT31 MAGEB2 MAGEB4 MORF4L1 MORF4L2 NOTCH2NLA PML REP15 SP100 TIMM8A TP53 TTC32 UBE2E3 XPA
Entrez ID		4115	1820
HPRD ID		02150	10343
Ensembl ID		ENSG00000120289	ENSG00000116017
Uniprot IDs		O15481	Q99856
PDB IDs			2KK0 4LJX
Enriched GO Terms of Interacting Partners?			Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Lens Fiber Cell Apoptotic Process Rb-E2F Complex Positive Regulation Of RNA Metabolic Process DNA Damage Response DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of RNA Metabolic Process Signal Transduction In Response To DNA Damage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Dimerization Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Cis-regulatory Region Sequence-specific DNA Binding Type II Interferon-mediated Signaling Pathway Regulation Of Gene Expression Regulation Of Apoptotic Process Regulation Of Cell Cycle Transcription Regulator Complex Regulation Of Fibroblast Proliferation Regulation Of Programmed Cell Death Regulation Of Macromolecule Biosynthetic Process Nucleus Negative Regulation Of Telomere Maintenance Via Telomerase PML Body Cellular Response To Stress Retinoic Acid Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Regulation Of Cellular Response To Stress DNA-binding Transcription Activator Activity Positive Regulation Of Macromolecule Metabolic Process Molecular Function Activator Activity Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription By RNA Polymerase II NuA4 Histone Acetyltransferase Complex Apoptotic Process Response To Light Stimulus RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of RNA Biosynthetic Process
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