USP51 and PJA1

Number of citations of the paper that reports this interaction (PMID 22626734)
2

Data Source:
BioGRID (enzymatic study)

		USP51	PJA1
Gene Name		ubiquitin specific peptidase 51	praja ring finger 1, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	SAGA Complex	Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Zinc Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Histone Deubiquitination Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process	Protein Ubiquitination Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: PJA1 USP15 USP21 USP28	36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440
Entrez ID		158880	64219
HPRD ID		07167	02335
Ensembl ID		ENSG00000247746	ENSG00000181191
Uniprot IDs		Q70EK9	Q8NG27
PDB IDs			2L0B
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Catabolic Process Protein Modification By Small Protein Removal Regulation Of Proteasomal Protein Catabolic Process Histone Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteolysis Cellular Macromolecule Catabolic Process Histone H2B Conserved C-terminal Lysine Deubiquitination Cellular Protein Modification Process Proteolysis Cellular Protein Metabolic Process Monoubiquitinated Protein Deubiquitination Histone Modification Regulation Of Cellular Protein Metabolic Process Pathway-restricted SMAD Protein Phosphorylation Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Protein Metabolic Process Chromatin Modification Chromatin Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To UV Chromosome Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Cellular Response To Light Stimulus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway
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