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SH2D4A and CASK
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
SH2D4A
CASK
Description
SH2 domain containing 4A
calcium/calmodulin dependent serine protein kinase
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Basement Membrane
Nucleus
Nuclear Lamina
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Membrane
Basolateral Plasma Membrane
Nuclear Matrix
Cell Junction
Vesicle
Presynaptic Membrane
Synapse
Ciliary Membrane
Cell Periphery
Schaffer Collateral - CA1 Synapse
Molecular Function
Protein Binding
Phosphatase Binding
Nucleotide Binding
GMP Kinase Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
Calmodulin Binding
ATP Binding
Kinase Activity
Transferase Activity
Neurexin Family Protein Binding
Protein Serine Kinase Activity
Biological Process
Negative Regulation Of Cell-matrix Adhesion
Cell Adhesion
Intracellular Protein Localization
Negative Regulation Of Keratinocyte Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
GMP Metabolic Process
GDP Metabolic Process
Regulation Of Neurotransmitter Secretion
Establishment Of Localization In Cell
Negative Regulation Of Wound Healing
Calcium Ion Import
Positive Regulation Of Calcium Ion Import
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Dopamine Neurotransmitter Release Cycle
Syndecan interactions
Nephrin family interactions
Neurexins and neuroligins
Neurexins and neuroligins
Assembly and cell surface presentation of NMDA receptors
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Formic acid
Fostamatinib
Diseases
FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS
Fasting plasma glucose (
32682390
)
Smooth-surface caries (
24556642
)
Urate levels in overweight individuals (
25811787
)
Urinary albumin excretion rate in type 1 diabetes (
24595857
)
Interacting Genes
73 interacting genes:
ALAS1
ARC
BLOC1S2
CADPS
CASK
CCDC172
CCDC88B
CDR2
CDR2L
CEP70
CEP76
CFAP53
DBNL
FCHO1
FCHSD2
FSD2
GOLGA2
GOLGA6L9
GPRASP2
GRAMD4
GRAP2
GRB2
HCLS1
HMBOX1
HOOK2
HSF2BP
IKZF1
KRT40
LDOC1
LZTS2
MAGEA11
MAGEA6
MBD3L1
MEOX2
MORN3
MRFAP1
MTUS2
NECAB2
NINL
NUTM1
OLIG1
PDE4DIP
PICK1
PLEKHG4
PNMA1
PRKAR1B
PSTPIP1
RINT1
SH3GL1
SH3RF1
SKAP1
SORBS2
SORBS3
SPAG5
STAM2
STX11
TACC1
TFIP11
TRAF2
TRIM23
TRIM27
TRIML2
TTC19
UBXN11
USHBP1
VPS52
WWOX
YPEL2
YPEL3
ZBTB16
ZMYND12
ZNF655
ZNF774
90 interacting genes:
AKAP9
APBA1
ATP2B4
BNIP3L
CADM1
CASKIN1
CDK9
CIMIP1
CNTNAP2
CNTNAP4
DDX54
DLG1
DLG4
DUSP3
ELL2
EPB41
EPS8
ERBIN
F11R
FCHSD2
FMR1
GCNT3
GLS2
GRIK2
GRIN2A
GTSE1
HGS
ID1
IL15RA
IL18
KCNA4
KCNJ12
KCNJ2
KCNJ4
KIF2A
KLC4
LIN7A
LIN7B
MAPRE1
MAPRE2
MARK2
MARS1
MED1
MLLT6
MLX
NDEL1
NPHS1
NRXN1
NRXN2
NRXN3
NTN4
P2RX7
PARD3B
PARD6G
PCBP2
PCM1
PKP2
PLK2
PPP4R3A
PRC1
PRKCI
PRKD2
PRKN
PRPF3
PTGS2
RAB3A
RBBP6
RBM10
RBM14
RBM5
RPA2
RPH3A
RSPH1
SDC1
SDC2
SDC3
SDC4
SF3B2
SH2D4A
SLAIN2
SRPK2
TANC1
TBR1
TIAM1
TRIM22
TSPYL2
UBC
WHRN
WNT7B
YWHAE
Entrez ID
63898
8573
HPRD ID
08340
02164
Ensembl ID
ENSG00000104611
ENSG00000147044
Uniprot IDs
Q9H788
A0A2R8YE77
A0A2U3TZM1
A0A7I2RJN6
O14936
PDB IDs
1KGD
1KWA
1ZL8
3C0G
3C0H
3C0I
3MFR
3MFS
3MFT
3MFU
3TAC
6KMH
7OAI
7OAJ
7OAK
7OAL
Enriched GO Terms of Interacting Partners
?
Protein Binding
Cytoplasm
Cytoskeleton Organization
Centrosome
Microtubule Cytoskeleton Organization
Cytoskeleton
Vesicle-mediated Transport
Microtubule-based Process
Regulation Of Cytoskeleton Organization
Establishment Of Localization In Cell
Positive Regulation Of Cytoskeleton Organization
Identical Protein Binding
Cytosol
Intracellular Transport
Organelle Organization
Neuroligin Family Protein Binding
Glutamatergic Synapse
PDZ Domain Binding
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Synapse
Cell Projection
Microtubule-based Process
Intracellular Protein Localization
Regulation Of Membrane Potential
Positive Regulation Of Cellular Component Biogenesis
Vocalization Behavior
Neurotransmitter Secretion
Learning
Cellular Component Assembly
Protein Localization To Cell Junction
Social Behavior
Cell Adhesion
Presynaptic Membrane
Microtubule Cytoskeleton Organization
Protein Localization To Synapse
Regulation Of Cytoskeleton Organization
Cytoskeleton Organization
Chemical Synaptic Transmission
Neurotransmitter Transport
Regulation Of System Process
Cell-cell Junction
Regulation Of Transport
MPP7-DLG1-LIN7 Complex
Trans-synaptic Signaling
Learning Or Memory
Regulation Of Monoatomic Ion Transport
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Presynaptic Modulation Of Chemical Synaptic Transmission
Synaptic Signaling
Establishment Or Maintenance Of Cell Polarity
Signal Release
Regulation Of Exosomal Secretion
Regulation Of Multicellular Organismal Process
Voltage-gated Potassium Channel Complex
Postsynaptic Membrane
Plasma Membrane
Neuromuscular Junction
Presynapse
Protein Kinase Binding
Regulation Of Biological Quality
Bicellular Tight Junction
Protein Localization To Membrane
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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