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SH2D4A and BLOC1S2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
SH2D4A
BLOC1S2
Description
SH2 domain containing 4A
biogenesis of lysosomal organelles complex 1 subunit 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Gamma-tubulin Complex
Nucleus
Cytoplasm
Mitochondrion
Lysosome
Lysosomal Membrane
Centrosome
Cytosol
Cytoskeleton
Membrane
BLOC-1 Complex
Cytoplasmic Side Of Lysosomal Membrane
BORC Complex
Axon Cytoplasm
Molecular Function
Protein Binding
Phosphatase Binding
Protein Binding
Gamma-tubulin Binding
Biological Process
Microtubule Nucleation
Anterograde Axonal Transport
Positive Regulation Of Cell Population Proliferation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Endosomal Transport
Neuron Projection Development
Lysosome Localization
Melanosome Organization
Positive Regulation Of DNA-templated Transcription
Anterograde Synaptic Vesicle Transport
Regulation Of Endosome Size
Platelet Dense Granule Organization
Regulation Of Lysosome Size
Organelle Transport Along Microtubule
Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS
Fasting plasma glucose (
32682390
)
Smooth-surface caries (
24556642
)
Urate levels in overweight individuals (
25811787
)
Urinary albumin excretion rate in type 1 diabetes (
24595857
)
Refractive error (
32231278
)
Interacting Genes
73 interacting genes:
ALAS1
ARC
BLOC1S2
CADPS
CASK
CCDC172
CCDC88B
CDR2
CDR2L
CEP70
CEP76
CFAP53
DBNL
FCHO1
FCHSD2
FSD2
GOLGA2
GOLGA6L9
GPRASP2
GRAMD4
GRAP2
GRB2
HCLS1
HMBOX1
HOOK2
HSF2BP
IKZF1
KRT40
LDOC1
LZTS2
MAGEA11
MAGEA6
MBD3L1
MEOX2
MORN3
MRFAP1
MTUS2
NECAB2
NINL
NUTM1
OLIG1
PDE4DIP
PICK1
PLEKHG4
PNMA1
PRKAR1B
PSTPIP1
RINT1
SH3GL1
SH3RF1
SKAP1
SORBS2
SORBS3
SPAG5
STAM2
STX11
TACC1
TFIP11
TRAF2
TRIM23
TRIM27
TRIML2
TTC19
UBXN11
USHBP1
VPS52
WWOX
YPEL2
YPEL3
ZBTB16
ZMYND12
ZNF655
ZNF774
36 interacting genes:
APP
ARFIP2
BFSP2
BLOC1S1
BLOC1S3
BLOC1S4
BLOC1S5
BLOC1S6
C8orf33
CCDC146
CCHCR1
CCNC
CTNNA3
DCTN2
ERP27
EXOC8
FAM161B
FAM9B
GADD45G
GEM
HMOX2
KRT26
MEST
P4HA3
PAM16
PICK1
RDH11
SH2D4A
SNAPIN
SSC5D
STX2
TNNT1
TRIML2
TTC3
WASHC1
WASHC3
Entrez ID
63898
282991
HPRD ID
08340
12526
Ensembl ID
ENSG00000104611
ENSG00000196072
Uniprot IDs
Q9H788
A0A087X1N6
F1T0F0
Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Binding
Cytoplasm
Cytoskeleton Organization
Centrosome
Microtubule Cytoskeleton Organization
Cytoskeleton
Vesicle-mediated Transport
Microtubule-based Process
Regulation Of Cytoskeleton Organization
Establishment Of Localization In Cell
Positive Regulation Of Cytoskeleton Organization
Identical Protein Binding
Cytosol
Intracellular Transport
Organelle Organization
Anterograde Synaptic Vesicle Transport
BLOC-1 Complex
Synaptic Vesicle Transport
Melanosome Organization
Pigment Granule Organization
Axo-dendritic Transport
Anterograde Axonal Transport
Vesicle Transport Along Microtubule
Vesicle Cytoskeletal Trafficking
Establishment Of Vesicle Localization
Axon Cytoplasm
Axonal Transport
Vesicle Localization
Organelle Localization
Organelle Transport Along Microtubule
Intracellular Transport
Transport Along Microtubule
Melanosome Transport
Cellular Localization
Establishment Of Melanosome Localization
Pigment Granule Transport
Cytoskeleton-dependent Intracellular Transport
Establishment Of Localization In Cell
Melanosome Localization
Pigment Granule Localization
Vesicle Organization
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Microtubule-based Transport
Microvesicle
Regulation Of Actin Nucleation
Plasma Membrane Bounded Cell Projection Organization
Endosome To Melanosome Transport
Microtubule-based Movement
Establishment Of Organelle Localization
Protein Transport
Cell Projection Organization
Secretion By Cell
Organelle Organization
Membrane Curvature Sensor Activity
Microtubule-based Process
Establishment Of Protein Localization
Secretion Of Lysosomal Enzymes
Neuron Projection Development
Exocytosis
Positive Regulation Of Pigment Cell Differentiation
Secretion
Regulation Of Lysosome Size
BORC Complex
Positive Regulation Of Developmental Pigmentation
Pigmentation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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