SH2D4A and SH3GL1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SH2D4A	SH3GL1
Gene Name		SH2 domain containing 4A	SH3-domain GRB2-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Podosome Cytoplasm Cell Junction Early Endosome Membrane Cell Projection
	Molecular Function	Protein Binding Phosphatase Binding	Protein Binding Lipid Binding Phosphatase Binding Identical Protein Binding GTPase Binding
	Biological Process	Negative Regulation Of Phosphatase Activity	Endocytosis Signal Transduction Central Nervous System Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16	26 interactors: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A GPKOW ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPT8 SH2D4A SH3D19 SH3GL2 SH3GL3 SYNJ1 VIM VPS37C YWHAZ
Entrez ID		63898	6455
HPRD ID		08340	03462
Ensembl ID		ENSG00000104611	ENSG00000141985
Uniprot IDs		Q9H788	Q6FGM0 Q99961
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Positive Regulation Of NK T Cell Differentiation G2/M Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Granulocyte Differentiation Mitotic Cell Cycle Immune System Process Positive Regulation Of Cytoskeleton Organization Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Cell Division Mitotic Cell Cycle Process Positive Regulation Of Cell-cell Adhesion Protein Complex Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Calcium Ion Import Actin Filament Organization Regulation Of T Cell Activation Cytoskeleton Organization Positive Regulation Of Cell Activation Protein K63-linked Ubiquitination Protein Trimerization Cellular Protein Complex Assembly Positive Regulation Of Immune System Process Regulation Of Organelle Organization Regulation Of Microtubule-based Process Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Actin Cytoskeleton Organization Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of Immune System Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Lymphocyte Activation Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cellular Localization Cell Cycle Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length	Vesicle-mediated Transport Positive Regulation Of Protein Autoubiquitination Endocytosis Regulation Of Protein Autoubiquitination Regulation Of Cellular Component Organization Protein Localization To Mitochondrion Regulation Of Cellular Localization Regulation Of Protein Ubiquitination Cellular Localization Cell Death Death Regulation Of Mitochondrial Fission Regulation Of Signaling Organelle Organization Regulation Of Mitochondrion Organization Membrane Organization Cell Part Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Viral Process Positive Regulation Of Proteolysis Entrainment Of Circadian Clock By Photoperiod Signaling Cell Development Virion Assembly Transport Apoptotic Process Cell Communication Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Protein Ubiquitination Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Programmed Cell Death Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Protein Catabolic Process Axon Guidance Synaptic Vesicle Endocytosis Generation Of Neurons Synaptic Vesicle Recycling Positive Regulation Of Organelle Organization Neuron Differentiation Organelle Localization Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Transport Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Neuron Projection Development Positive Regulation Of Synaptic Vesicle Uncoating
Tagcloud ?			antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Difference) ?			antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Intersection) ?