CASK and PCM1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CASK	PCM1
Gene Name		calcium/calmodulin-dependent serine protein kinase (MAGUK family)	pericentriolar material 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Presynaptic Membrane Ciliary Membrane	Pericentriolar Material Cytoplasm Centrosome Cytosol Membrane Nonmotile Primary Cilium Nuclear Membrane Centriolar Satellite Ciliary Basal Body Protein Complex
	Molecular Function	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Negative Regulation Of Keratinocyte Proliferation Extracellular Matrix Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide Phosphorylation Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Negative Regulation Of Neurogenesis Centrosome Organization Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Maintenance
Pathways		Syndecan interactions Nephrin interactions Non-integrin membrane-ECM interactions	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Economic and political preferences ( 22566634)
Protein-Protein Interactions		60 interactors: APBA1 ATP2B4 BNIP3L C16orf70 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DFNB31 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBB2IP F11R FCHSD2 GCNT3 GLS2 GRIK2 GRIN2A HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 LIN7A LIN7B MARS MLLT6 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARK2 PCBP2 PCM1 PLK2 PRKD2 PTGS2 RAB3A RPH3A SDC1 SDC2 SDC3 SDC4 SH2D4A SMEK1 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WNT7B	17 interactors: ABI2 BBS4 CASK CCDC53 CEP131 CEP72 E2F4 EPS8 EXOC8 HAP1 ING5 KIAA0368 KRT15 KRT19 PCNT TTC8 YWHAQ
Entrez ID		8573	5108
HPRD ID		02164	02624
Ensembl ID		ENSG00000147044	ENSG00000078674
Uniprot IDs		O14936	A2RUU9 E7ETA6 Q15154
PDB IDs		1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Signaling Cell Communication Cell-cell Signaling Regulation Of Neurotransmitter Levels Learning Vocalization Behavior Neurotransmitter Secretion Neurotransmitter Transport Single-organism Behavior Learning Or Memory Behavior Cognition Establishment Or Maintenance Of Apical/basal Cell Polarity Cellular Protein Localization Cellular Localization Response To External Stimulus Anatomical Structure Development Social Behavior Cellular Component Assembly Regulation Of Synaptic Transmission System Development Regulation Of Cellular Component Organization Response To Stimulus Synapse Organization Regulation Of Grooming Behavior Regulation Of Organelle Organization Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Abiotic Stimulus Multicellular Organismal Development Regulation Of Ion Transport Protein Localization Secretion By Cell Membrane Depolarization Developmental Process Anatomical Structure Morphogenesis Neurological System Process Maintenance Of Apical/basal Cell Polarity Cell Adhesion Membrane Organization Receptor Localization To Synapse Regulation Of Cellular Localization Synapse Assembly Regulation Of Signaling Positive Regulation Of Transport Angiogenesis Regulation Of Intracellular Signal Transduction Secretion Positive Regulation Of Exosomal Secretion	Organelle Organization Cilium Organization Cilium Morphogenesis Mitotic Cell Cycle Positive Regulation Of Cilium Assembly Sensory Processing Cell Cycle Process Mitotic Cell Cycle Process Cilium Assembly Cell Projection Organization Microtubule-based Process Organelle Assembly Cell Cycle Regulation Of Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Projection Assembly Regulation Of Microtubule-based Movement Cellular Protein Complex Localization Rac Protein Signal Transduction Organ Development Nonmotile Primary Cilium Assembly G2/M Transition Of Mitotic Cell Cycle Cytoskeleton Organization Protein Complex Localization Anatomical Structure Development Regulation Of Cilium Assembly Positive Regulation Of Transport Positive Regulation Of Organelle Assembly Brain Development Positive Regulation Of Organelle Organization Cellular Component Assembly Head Development Regulation Of Intracellular Transport Cell Projection Morphogenesis Regulation Of Microtubule-based Process Forebrain Development Cell Part Morphogenesis Developmental Process Movement Of Cell Or Subcellular Component Olfactory Bulb Development Brain Morphogenesis Central Nervous System Development Multicellular Organismal Development Olfactory Lobe Development Eye Photoreceptor Cell Differentiation Positive Regulation Of Intracellular Transport Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Positive Regulation Of Neurotrophin Production
Tagcloud ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo	9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib termed usually
Tagcloud (Difference) ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic zo	9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib usually
Tagcloud (Intersection) ?		termed