CASK and F11R

Number of citations of the paper that reports this interaction (PMID 10856295)
63

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CASK	F11R
Gene Name		calcium/calmodulin-dependent serine protein kinase (MAGUK family)	F11 receptor
Image
Gene Ontology Annotations	Cellular Component	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Presynaptic Membrane Ciliary Membrane	Plasma Membrane Cell-cell Junction Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Slit Diaphragm Extracellular Vesicular Exosome
	Molecular Function	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding	Protein Binding PDZ Domain Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Negative Regulation Of Keratinocyte Proliferation Extracellular Matrix Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide Phosphorylation Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus	Inflammatory Response Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Blood Coagulation Response To Radiation Viral Process Extracellular Matrix Organization Actomyosin Structure Organization Positive Regulation Of Rap GTPase Activity Negative Regulation Of Rho GTPase Activity Cell Junction Assembly Cell-cell Junction Organization Positive Regulation Of Blood Pressure Intestinal Absorption Leukocyte Migration Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Regulation Of Actin Cytoskeleton Reorganization
Pathways		Syndecan interactions Nephrin interactions Non-integrin membrane-ECM interactions	Loss of Function of TGFBR2 in Cancer Cell junction organization TGFBR2 MSI Frameshift Mutants in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer Tight junction interactions Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Cell surface interactions at the vascular wall Cell-cell junction organization Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer Integrin cell surface interactions SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		60 interactors: APBA1 ATP2B4 BNIP3L C16orf70 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DFNB31 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBB2IP F11R FCHSD2 GCNT3 GLS2 GRIK2 GRIN2A HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 LIN7A LIN7B MARS MLLT6 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARK2 PCBP2 PCM1 PLK2 PRKD2 PTGS2 RAB3A RPH3A SDC1 SDC2 SDC3 SDC4 SH2D4A SMEK1 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WNT7B	16 interactors: ASIP BDNF CASK CGN CSNK2A1 F2RL2 ITGAL MLLT4 MPDZ PARD3 PEX19 PICK1 PRKCA PTPRB SGTA TJP1
Entrez ID		8573	50848
HPRD ID		02164	12038
Ensembl ID		ENSG00000147044	ENSG00000158769
Uniprot IDs		O14936	B7Z941 Q6FIB4 Q9Y624
PDB IDs		1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC	1NBQ 3EOY 3TSZ
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Signaling Cell Communication Cell-cell Signaling Regulation Of Neurotransmitter Levels Learning Vocalization Behavior Neurotransmitter Secretion Neurotransmitter Transport Single-organism Behavior Learning Or Memory Behavior Cognition Establishment Or Maintenance Of Apical/basal Cell Polarity Cellular Protein Localization Cellular Localization Response To External Stimulus Anatomical Structure Development Social Behavior Cellular Component Assembly Regulation Of Synaptic Transmission System Development Regulation Of Cellular Component Organization Response To Stimulus Synapse Organization Regulation Of Grooming Behavior Regulation Of Organelle Organization Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Abiotic Stimulus Multicellular Organismal Development Regulation Of Ion Transport Protein Localization Secretion By Cell Membrane Depolarization Developmental Process Anatomical Structure Morphogenesis Neurological System Process Maintenance Of Apical/basal Cell Polarity Cell Adhesion Membrane Organization Receptor Localization To Synapse Regulation Of Cellular Localization Synapse Assembly Regulation Of Signaling Positive Regulation Of Transport Angiogenesis Regulation Of Intracellular Signal Transduction Secretion Positive Regulation Of Exosomal Secretion	Cell Junction Assembly Cell-cell Junction Organization Cell-cell Junction Assembly Establishment Of Endothelial Intestinal Barrier Signal Transduction Epithelial Cell Development Membrane Organization Cell-cell Signaling Signaling Cell Communication Anatomical Structure Development Protein Localization To Membrane Cell Development Cellular Response To Stimulus Developmental Process Establishment Of Endothelial Barrier Epithelial Cell Differentiation Cell Surface Receptor Signaling Pathway Endothelial Cell Development Tight Junction Assembly Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Epithelial Cell Morphogenesis Epithelium Development Anatomical Structure Morphogenesis Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Wound Healing Response To Growth Factor Receptor Clustering Tissue Development G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Anesthetic Negative Regulation Of Lipid Binding Positive Regulation Of Dense Core Granule Biogenesis Response To Fluoxetine Response To L-glutamate Cell Differentiation Cell Adhesion Chaperone-mediated Protein Folding Negative Regulation Of Synaptic Transmission Cellular Response To Organic Substance Response To Wounding Response To Stimulus Locomotion Apical Junction Assembly Cell Morphogenesis Involved In Differentiation Endothelial Cell Differentiation Cellular Response To Carbohydrate Stimulus Multicellular Organismal Development
Tagcloud ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Difference) ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Intersection) ?