RPLP1 and MAP1LC3B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPLP1	MAP1LC3B
Gene Name		ribosomal protein, large, P1	microtubule-associated protein 1 light chain 3 beta
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding Microtubule Binding GABA Receptor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Major depressive disorder ( 22472876)
Protein-Protein Interactions		34 interactors: ANKRD13B ASCC2 ATP5J2 BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGOL1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6	50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2
Entrez ID		6176	81631
HPRD ID		01611	14358
Ensembl ID		ENSG00000137818	ENSG00000140941
Uniprot IDs		P05386	H6UMI0 Q658J6 Q9GZQ8
PDB IDs		2LBF 3J3B 4BEH	1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Growth Factor Negative Regulation Of MAPK Cascade Cellular Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Catabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cell Cycle 'de Novo' Posttranslational Protein Folding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Spermidine Acetylation Superior Temporal Gyrus Development Golgi Vesicle Docking Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle 'de Novo' Protein Folding TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Cycle Phase Transition Cellular Response To Heat Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation
Tagcloud ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?