RPLP1 and RPLP2

Number of citations of the paper that reports this interaction (PMID 10856704)
11

Data Source:
HPRD (two hybrid)

		RPLP1	RPLP2
Gene Name		ribosomal protein, large, P1	ribosomal protein, large, P2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: ANKRD13B ASCC2 ATP5J2 BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGOL1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6	4 interactors: ADRBK1 MAPK8 RPLP1 YWHAQ
Entrez ID		6176	6181
HPRD ID		01611	01612
Ensembl ID		ENSG00000137818
Uniprot IDs		P05386	P05387
PDB IDs		2LBF 3J3B 4BEH	1S4J 2JDL 2LBF 2W1O 3J3B 4BEH
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Growth Factor Negative Regulation Of MAPK Cascade Cellular Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Catabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cell Cycle 'de Novo' Posttranslational Protein Folding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Spermidine Acetylation Superior Temporal Gyrus Development Golgi Vesicle Docking Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle 'de Novo' Protein Folding TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Cycle Phase Transition Cellular Response To Heat Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Peptidyl-threonine Phosphorylation Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Positive Regulation Of Transport Peptidyl-serine Phosphorylation Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Cellular Localization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Intracellular Transport JUN Phosphorylation Positive Regulation Of Deacetylase Activity Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Striated Muscle Contraction Apoptotic Signaling Pathway Regulation Of The Force Of Heart Contraction By Chemical Signal Tachykinin Receptor Signaling Pathway Positive Regulation Of Organelle Organization Positive Regulation Of Catecholamine Secretion Protein Targeting Regulation Of Intracellular Transport Cellular Response To Nitric Oxide G-protein Coupled Acetylcholine Receptor Signaling Pathway Response To Nitric Oxide Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Negative Regulation Of Muscle Contraction Positive Regulation Of Programmed Cell Death Response To Growth Factor Cellular Response To Reactive Nitrogen Species Negative Regulation Of Heart Contraction Positive Regulation Of Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of The Force Of Heart Contraction Regulation Of Signal Transduction Regulation Of Histone Deacetylation Substantia Nigra Development Regulation Of Protein Localization Innate Immune Response Receptor Internalization Membrane Organization Programmed Necrotic Cell Death Necrotic Cell Death
Tagcloud ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded	18s actbeta assume atp5b august beta2m canx cited contrasting cyc1 february gapdh gus healing housekeeping july normalization normalizing pig qpcr sdha stably studying tbp ubc unwounded wound wounded ywhaz
Tagcloud (Difference) ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded	18s actbeta assume atp5b august beta2m canx cited contrasting cyc1 february gapdh gus healing housekeeping july normalization normalizing pig qpcr sdha stably studying tbp ubc unwounded wound wounded ywhaz
Tagcloud (Intersection) ?