RPLP1 and CDK2AP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPLP1	CDK2AP2
Gene Name		ribosomal protein, large, P1	cyclin-dependent kinase 2 associated protein 2
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: ANKRD13B ASCC2 ATP5J2 BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGOL1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6	17 interactors: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS YIF1A ZBTB48
Entrez ID		6176	10263
HPRD ID		01611	13242
Ensembl ID		ENSG00000137818	ENSG00000167797
Uniprot IDs		P05386	O75956 Q6IAV4
PDB IDs		2LBF 3J3B 4BEH	2M1L
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Growth Factor Negative Regulation Of MAPK Cascade Cellular Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Catabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cell Cycle 'de Novo' Posttranslational Protein Folding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Spermidine Acetylation Superior Temporal Gyrus Development Golgi Vesicle Docking Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle 'de Novo' Protein Folding TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Cycle Phase Transition Cellular Response To Heat Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Gene Expression Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclease Activity Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Platelet Degranulation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Tryptophanyl-tRNA Aminoacylation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Complement Activation, Lectin Pathway Cellular Aromatic Compound Metabolic Process Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Metabolic Process Regulation Of Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Multicellular Organism Growth Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Protein Modification Process Cholesterol Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition L-proline Biosynthetic Process Sterol Metabolic Process Response To Unfolded Protein Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Protein Metabolic Process Axon Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Phosphorylation MRNA Metabolic Process Histone H3-K9 Demethylation Response To Endoplasmic Reticulum Stress Positive Regulation Of Ran GTPase Activity Positive Regulation Of Granulocyte Differentiation
Tagcloud ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded
Tagcloud (Difference) ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded
Tagcloud (Intersection) ?