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RPL7A and SOCS3
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
RPL7A
SOCS3
Description
ribosomal protein L7a
suppressor of cytokine signaling 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Cytosol
Ribosome
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Synapse
Ribonucleoprotein Complex
Cytosol
Cytoplasmic Side Of Plasma Membrane
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Cadherin Binding
Phosphotyrosine Residue Binding
Protein Kinase Inhibitor Activity
Cytokine Receptor Binding
Protein Binding
Protein Tyrosine Kinase Inhibitor Activity
MiRNA Binding
Biological Process
Maturation Of LSU-rRNA
Cytoplasmic Translation
Translation
Ribosome Biogenesis
Signal Transduction
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Signal Transduction
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Cell Differentiation
Intracellular Signal Transduction
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Differentiation
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Inflammatory Response
Branching Involved In Labyrinthine Layer Morphogenesis
Placenta Blood Vessel Development
Interleukin-6-mediated Signaling Pathway
T-helper 17 Cell Lineage Commitment
Cellular Response To Interleukin-17
Cellular Response To Leukemia Inhibitory Factor
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Interleukin-6 signaling
Signaling by Leptin
Interleukin-4 and Interleukin-13 signaling
Interferon gamma signaling
Regulation of IFNG signaling
PTK6 Activates STAT3
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Neddylation
Interferon alpha/beta signaling
Regulation of IFNA/IFNB signaling
Signaling by CSF3 (G-CSF)
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Growth hormone receptor signaling
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Malaria (
31844061
)
Asthma (
32296059
)
Blood trace element (Se levels) (
23720494
)
Creatine kinase levels (
29403010
)
Interacting Genes
9 interacting genes:
CCDC47
CTBP2
DUX4
MKNK2
POLR2M
SGO1
SOCS3
STAU1
USP7
66 interacting genes:
ABL1
ACADVL
APP
AR
BCL10
BIK
BLK
CAVIN1
CSF1R
CSF3R
CSNK1E
CUEDC2
CXCR4
EGFR
ELOB
ELOC
EPOR
ERBB2
ERBB3
ERBB4
GAB1
GFRA1
GHR
HIVEP1
IGF1R
IL12RB2
IL2RB
IL6ST
INSR
IRF7
IRS1
IRS2
JAK1
JAK2
JAK3
KIAA1958
KIT
LEPR
MAP1S
MAPK11
MAPK6
MET
MEX3C
NFATC2
NME4
PDPK1
PIN1
PPP3CB
PRLR
PTK2
PTPN11
RASA1
RBMX
RNF31
RNF7
RPL7A
SH2D2A
SOCS2
TES
TFDP1
TFR2
TRDN
TXK
TXNDC11
YES1
YWHAQ
Entrez ID
6130
9021
HPRD ID
01712
05006
Ensembl ID
ENSG00000148303
ENSG00000184557
Uniprot IDs
P62424
O14543
Q6FI39
PDB IDs
4UG0
4V6X
5AJ0
5LKS
5T2C
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
6ZVK
7A01
7BHP
7F5S
7OW7
7QVP
7XNX
7XNY
7ZJW
7ZJX
8A3D
8FKP
8FKQ
8FKR
8FKS
8FKT
8FKU
8FKV
8FKW
8FKX
8FKY
8FKZ
8FL2
8FL3
8FL4
8FL6
8FL7
8FL9
8FLA
8FLB
8FLC
8FLD
8FLE
8FLF
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IDT
8IDY
8IE3
8IFD
8IFE
8INE
8INF
8INK
8IPD
8IPX
8IPY
8IR1
8IR3
8JDJ
8JDK
8JDL
8JDM
8K2C
8OHD
8OJ0
8OJ5
8OJ8
8P2K
8QFD
8QOI
8QYX
8RL2
8UKB
8XSX
8XSY
8XSZ
8Y0W
8Y0X
8YOO
8YOP
9C3H
9G8M
9GMO
Enriched GO Terms of Interacting Partners
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Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Protein Tyrosine Kinase Activity
Receptor Complex
Signal Transduction
Protein Kinase Activity
Kinase Activity
Cytokine-mediated Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Protein Phosphorylation
Positive Regulation Of Cell Communication
Cytokine Binding
Phosphorylation
Negative Regulation Of Programmed Cell Death
Peptidyl-tyrosine Phosphorylation
Intracellular Signal Transduction
Positive Regulation Of Signaling
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Population Proliferation
Epidermal Growth Factor Receptor Signaling Pathway
Growth Hormone Receptor Signaling Pathway
Non-membrane Spanning Protein Tyrosine Kinase Activity
Cytokine Receptor Activity
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
ERBB Signaling Pathway
Cell Surface Receptor Signaling Pathway Via STAT
Regulation Of Cell Population Proliferation
Transmembrane Receptor Protein Tyrosine Kinase Activity
Positive Regulation Of Metabolic Process
Positive Regulation Of Multicellular Organismal Process
Regulation Of Multicellular Organismal Process
Negative Regulation Of Apoptotic Process
External Side Of Plasma Membrane
Regulation Of Programmed Cell Death
Protein Modification Process
Erythropoietin-mediated Signaling Pathway
Developmental Process
Positive Regulation Of Intracellular Signal Transduction
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Regulation Of Immune System Process
Intracellular Signaling Cassette
Cell Differentiation
Positive Regulation Of Cell Motility
Cellular Developmental Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Communication
Positive Regulation Of Locomotion
Protein Autophosphorylation
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Tagcloud (Intersection)
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