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RBBP4 and H3C14
Number of citations of the paper that reports this interaction (PubMedID
12628926
)
40
Data Source:
HPRD
(in vitro)
RBBP4
H3C14
Description
RB binding protein 4, chromatin remodeling factor
H3 clustered histone 14
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytosol
NuRD Complex
NURF Complex
Protein-containing Complex
CAF-1 Complex
ESC/E(Z) Complex
Sin3-type Complex
ATPase Complex
Chromatin
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Chromosome
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Protein Binding
ATP-dependent Activity, Acting On DNA
Nucleosomal DNA Binding
Histone Binding
Histone Deacetylase Binding
DNA Binding
Chromatin Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Replication
DNA Repair
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Chromatin Assembly
Chromatin Remodeling
Regulation Of DNA-templated Transcription
DNA Damage Response
Brain Development
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Fate Specification
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Stem Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Nucleosome Assembly
Gene Expression
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
Cyclin A:Cdk2-associated events at S phase entry
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Regulation of endogenous retroelements by KRAB-ZFP proteins
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Assembly of the ORC complex at the origin of replication
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Factors involved in megakaryocyte development and platelet production
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Interacting Genes
59 interacting genes:
AEBP2
ANXA7
ARMC12
BRCA1
BRMS1
BRMS1L
CDKN1A
CHAF1B
CREB1
CREBBP
CYTOR
DDB1
DHX30
ESR1
EXOSC8
FOXK2
H1-1
H2AC20
H3-4
H3C1
H3C14
H4C14
H4C16
HDAC1
HDAC2
HDAC3
HDAC4
HMOX2
ING1
KPNA5
LIN9
LMNA
MBD2
MBD3
MTA1
MTA2
NR2E3
PRDM16
RB1
RBBP7
RBP1
RPN1
RPN2
RYBP
SALL4
SAP30
SIN3A
SMN1
SNCA
SP1
SP3
SPEN
STAT5B
SUMO2
SUV39H1
TK1
TSSK3
USP7
XRCC6
66 interacting genes:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CBX2
CBX4
CBX6
CBX7
CBX8
CDCA8
CDK8
CHUK
DDB2
DNAJC9
DNMT3L
EHMT2
ELP3
EP300
HDGFL2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
NAP1L4
NASP
NCOA6
NRDC
NSD2
PHF21A
PIM1
PKN1
PRMT6
PTMA
PWWP3A
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
Entrez ID
5928
126961
HPRD ID
04232
11822
Ensembl ID
ENSG00000162521
ENSG00000203811
Uniprot IDs
Q09028
Q71DI3
PDB IDs
2XU7
3GFC
4PBY
4PBZ
4PC0
4R7A
5FXY
5VTB
5WAI
5WAK
5XWR
5XXQ
5Y1U
6BW3
6BW4
6C23
6C24
6G16
6NQ3
6WKR
6ZRC
6ZRD
7AOA
7KSO
7KSR
7KTP
7M40
7N40
7R1D
7Y5K
7Y5L
7Y5O
7Y5U
7Y5V
8EQV
8FYH
8IQF
8IQG
8T9G
8TAS
8TB9
8TX8
8VMI
8VML
8VNV
8VNZ
9C8U
9DCH
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
5B0Y
5B0Z
5B40
5BO0
5CIU
5VAC
6ACE
6FML
6T79
6T7A
6T7B
6T7C
6T7D
6X59
6X5A
6XJD
6Y5D
6Y5E
7BQZ
7BU9
7JO9
7JOA
7JZV
7PET
7PEU
7PEV
7PEW
7PEX
7PEY
7PEZ
7PF0
7PF2
7PF3
7PF4
7PF5
7PF6
7PFA
7PFC
7PFD
7PFE
7PFF
7PFT
7PFU
7PFV
7PFW
7PFX
7TAN
7U50
7U51
7U52
7U53
7UV9
7UVA
7XCR
7XCT
7XD0
7YRD
8AAG
8ATF
8AV6
8GRQ
8HQY
8HR1
8JLB
8JLD
8OL1
8VMJ
8VMN
8VO0
8VOB
8VWS
8VWT
8VWU
8VWV
8X7I
8X7J
8X7K
9DWF
9DWG
9DWH
9DWI
9DWJ
9DWK
9DWL
9DWM
9GMK
9GMR
9IPU
Enriched GO Terms of Interacting Partners
?
Chromatin Remodeling
Chromatin Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Nucleus
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Heterochromatin Formation
Sin3-type Complex
Negative Regulation Of Stem Cell Population Maintenance
DNA Binding
Histone Deacetylase Complex
NuRD Complex
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Transcription Repressor Complex
Regulation Of RNA Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Rhythmic Process
Chromatin Binding
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Macromolecule Metabolic Process
Protein-containing Complex
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Fate Specification
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Stem Cell Population Maintenance
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Regulation Of Developmental Process
Chromatin
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Histone Deacetylase Binding
Chromosome
Chromatin Organization
Chromatin Remodeling
Nucleoplasm
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleus
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Chromatin Binding
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Metabolic Process
Chromosome
Positive Regulation Of Biosynthetic Process
Histone Binding
Histone Methyltransferase Complex
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Histone H3K4 Monomethyltransferase Activity
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Histone H3K4 Trimethyltransferase Activity
Transcription Coactivator Activity
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Chromatin
Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Transferase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Histone H3 Methyltransferase Activity
Negative Regulation Of Biosynthetic Process
P53 Binding
Regulation Of Metaphase Plate Congression
Histone H3K4 Methyltransferase Activity
Methylation
Methyltransferase Activity
Acetyltransferase Activity
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