PTPRC and IRS1

  • Number of citations of the paper that reports this interaction (PMID 8557683)
  • 2
  • Data Source:
  • HPRD (in vivo)

PTPRC

IRS1

Gene Name protein tyrosine phosphatase, receptor type, C insulin receptor substrate 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions 43 interactors: ANP32A CD1D CD2 CD22 CD247 CD28 CD4 CD8A CSNK2A1 CSNK2A2 CXCR4 DPP4 EZR FCGR3A FYN GANAB GRB2 IFNAR1 INSR IRS1 ITGAL JAK1 JAK2 JAK3 LCK LCP2 LGALS1 LSM1 LYN MBL2 PAEP PPFIA1 PPFIBP2 PRKCSH PTPN6 PTPRCAP RASA1 RNF11 SEMA4D SKAP1 TYK2 UHRF2 ZAP70 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 5788 3667
HPRD ID 01050 00943
Ensembl ID ENSG00000081237 ENSG00000169047
Uniprot IDs M9MML4 P08575 P35568
PDB IDs 1YGR 1YGU 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abl  adaptor  bcr  cd45  chemistry  cief  cml  combines  crkl  describes  detect  example  focusing  isoelectric  limit  linking  lysate  nanocapillary  nanogram  nl  pg  protocol  ptyr207  quantities  reproducible  screen  throughput  tkis  uv 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
abl  adaptor  bcr  cd45  chemistry  cief  cml  combines  crkl  describes  detect  example  focusing  isoelectric  limit  linking  lysate  nanocapillary  nanogram  nl  pg  protocol  ptyr207  quantities  reproducible  screen  throughput  tkis  uv 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?