IRS1 and IL4R

  • Number of citations of the paper that reports this interaction (PMID 8599766)
  • 21
  • Data Source:
  • HPRD (in vivo)

IRS1

IL4R

Gene Name insulin receptor substrate 1 interleukin 4 receptor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ 22 interactors: ARIH2 CD40 DOK2 FES GNB2L1 HGS IL13 IL13RA1 IL2RG IL4 INPP5D IRS1 IRS2 JAK1 JAK2 JAK3 PRKCZ PTPN11 PTPN6 SHC1 SOCS5 STAT6
Entrez ID 3667 3566
HPRD ID 00943 00990
Ensembl ID ENSG00000169047 ENSG00000077238
Uniprot IDs P35568 B2RBY1 B4E076 P24394
PDB IDs 1IRS 1K3A 1QQG 2Z8C 1IAR 1IRS 1ITE 3BPL 3BPN 3BPO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
4ps  ba  compatible  coupling  depend  equimolar  exclusive  f3  heterodimerization  i4r  il2  il2r  il7  il9  immunoblotting  jak1  jak3  manifest  mutational  phosphotyrosine  preferential  premyeloid  share  stably  subordinate  tf  tyk2  vigorous 
Tagcloud (Difference) ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
4ps  ba  compatible  coupling  depend  equimolar  exclusive  f3  heterodimerization  i4r  il2  il2r  il7  il9  immunoblotting  jak1  jak3  manifest  mutational  phosphotyrosine  preferential  premyeloid  share  stably  subordinate  tf  tyk2  vigorous 
Tagcloud (Intersection) ?