IRS1 and ROCK1

  • Number of citations of the paper that reports this interaction (PMID 11739394)
  • 35
  • Data Source:
  • HPRD (in vivo, in vitro)

IRS1

ROCK1

Gene Name insulin receptor substrate 1 Rho-associated, coiled-coil containing protein kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ 32 interactors: ADD1 ARHGAP24 C6orf165 CASP3 CASP7 CDC25A CDC34 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LMO2 MAGEB4 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TSG101 VIM
Entrez ID 3667 6093
HPRD ID 00943 03414
Ensembl ID ENSG00000169047
Uniprot IDs P35568 Q13464
PDB IDs 1IRS 1K3A 1QQG 2Z8C 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  rhoa  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Difference) ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  rhoa  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Intersection) ?