IRS1 and GRB14

  • Number of citations of the paper that reports this interaction (PMID 9748281)
  • 23
  • Data Source:
  • HPRD (in vivo, two hybrid)

IRS1

GRB14

Gene Name insulin receptor substrate 1 growth factor receptor-bound protein 14
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ 14 interactors: CDC5L DAPK3 EGFR FGFR1 IGF1R INSR IRS1 MAP3K14 PDGFRA PDGFRB PRKCZ SQSTM1 TEK TNKS2
Entrez ID 3667 2888
HPRD ID 00943 03313
Ensembl ID ENSG00000169047 ENSG00000115290
Uniprot IDs P35568 B7Z7F9 Q14449
PDB IDs 1IRS 1K3A 1QQG 2Z8C 2AUG 2AUH 4K81
Enriched GO Terms of Interacting Partners?
Tagcloud ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
adapter  appears  avidly  bear  bps  conversely  denote  domain  domains  dramatically  existence  grb10  grb7  homology  interact  interaction  interacts  ir  location  loop  obvious  paired  pleckstrin  resemblance  sh2  summary  unidentified  y1150f  y1151f 
Tagcloud (Difference) ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
adapter  appears  avidly  bear  bps  conversely  denote  domain  domains  dramatically  existence  grb10  grb7  homology  interact  interaction  interacts  ir  location  loop  obvious  paired  pleckstrin  resemblance  sh2  summary  unidentified  y1150f  y1151f 
Tagcloud (Intersection) ?