Gene Name |
protein tyrosine phosphatase, receptor type, C |
dipeptidyl-peptidase 4 |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Atorvastatin
- Sitagliptin
- 2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One
- 5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine
- Alpha-D-Mannose
- (2s)-Pyrrolidin-2-Ylmethylamine
- Iodo-Phenylalanine
- Diisopropylphosphono Group
- 1-(1-phenylcyclopentyl)methylamine
- (S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
- Vildagliptin
- Alogliptin
- Saxagliptin
- (1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE
- N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE
- (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine
- (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine
- (3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine
- (7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c\']dipyridin-7-amine
- (2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE
- (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
- (2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
- (2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE
- (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE
- (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE
- 4\'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide
- (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine
- 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile
- (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE
- METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE
- (1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE
- 1-biphenyl-2-ylmethanamine
- (1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile
- (2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE
- (3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE
- N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE
- (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE
- (3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE
- 1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE
- (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE
- (2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
- (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE
- 2-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidine
- N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide
- (3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE
- 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM
- 7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE
- 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE
- 4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE
- 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE
- Linagliptin
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Diseases |
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GWAS |
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Protein-Protein Interactions |
43 interactors:
ANP32A
CD1D
CD2
CD22
CD247
CD28
CD4
CD8A
CSNK2A1
CSNK2A2
CXCR4
DPP4
EZR
FCGR3A
FYN
GANAB
GRB2
IFNAR1
INSR
IRS1
ITGAL
JAK1
JAK2
JAK3
LCK
LCP2
LGALS1
LSM1
LYN
MBL2
PAEP
PPFIA1
PPFIBP2
PRKCSH
PTPN6
PTPRCAP
RASA1
RNF11
SEMA4D
SKAP1
TYK2
UHRF2
ZAP70
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16 interactors:
ADA
CCL11
CCL22
CCL3L1
CCL5
CD4
CPAMD8
CXCL10
CXCL11
CXCL12
CXCL9
CXCR4
DKK1
FAP
GRP
PTPRC
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Entrez ID |
5788 |
1803 |
HPRD ID |
01050 |
02187 |
Ensembl ID |
ENSG00000081237
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ENSG00000197635
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Uniprot IDs |
M9MML4
P08575
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P27487
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PDB IDs |
1YGR
1YGU
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1J2E
1N1M
1NU6
1NU8
1PFQ
1R9M
1R9N
1RWQ
1TK3
1TKR
1U8E
1W1I
1WCY
1X70
2AJL
2BGN
2BGR
2BUB
2FJP
2G5P
2G5T
2G63
2HHA
2I03
2I78
2IIT
2IIV
2JID
2OAG
2OGZ
2OLE
2ONC
2OPH
2OQI
2OQV
2P8S
2QJR
2QKY
2QOE
2QT9
2QTB
2RGU
2RIP
3BJM
3C43
3C45
3CCB
3CCC
3D4L
3EIO
3F8S
3G0B
3G0C
3G0D
3G0G
3H0C
3HAB
3HAC
3KWF
3KWJ
3NOX
3O95
3O9V
3OC0
3OPM
3Q0T
3Q8W
3QBJ
3SWW
3SX4
3VJK
3VJL
3VJM
3W2T
4A5S
4DSA
4DSZ
4DTC
4G1F
4JH0
4KR0
4L72
4LKO
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
abl
adaptor
bcr
cd45
chemistry
cief
cml
combines
crkl
describes
detect
example
focusing
isoelectric
limit
linking
lysate
nanocapillary
nanogram
nl
pg
protocol
ptyr207
quantities
reproducible
screen
throughput
tkis
uv
|
albuminuria
ameliorate
bioavailability
capability
dipeptidyl
english
experimentally
glp
indirectly
insufficient
interfere
journals
language
march
microalbuminuria
microangiopathy
microvascular
modifying
nephropathy
neuropathy
nonincretin
peer
peptidase
preliminary
retinopathy
retrieved
scanned
ulcer
|
Tagcloud (Difference) ? |
abl
adaptor
bcr
cd45
chemistry
cief
cml
combines
crkl
describes
detect
example
focusing
isoelectric
limit
linking
lysate
nanocapillary
nanogram
nl
pg
protocol
ptyr207
quantities
reproducible
screen
throughput
tkis
uv
|
albuminuria
ameliorate
bioavailability
capability
dipeptidyl
english
experimentally
glp
indirectly
insufficient
interfere
journals
language
march
microalbuminuria
microangiopathy
microvascular
modifying
nephropathy
neuropathy
nonincretin
peer
peptidase
preliminary
retinopathy
retrieved
scanned
ulcer
|
Tagcloud (Intersection) ? |
|