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PTPRC
Gene Name
protein tyrosine phosphatase, receptor type, C
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
External Side Of Plasma Membrane
Membrane
Membrane Raft
Extracellular Vesicular Exosome
Molecular Function
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Kinase Binding
Biological Process
Negative Regulation Of T Cell Mediated Cytotoxicity
Negative Regulation Of Cytokine-mediated Signaling Pathway
Hematopoietic Progenitor Cell Differentiation
Immunoglobulin Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Protein Dephosphorylation
Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration
Cell Surface Receptor Signaling Pathway
Axon Guidance
Dephosphorylation
T Cell Differentiation
Positive Regulation Of B Cell Proliferation
Peptidyl-tyrosine Dephosphorylation
B Cell Proliferation
Positive Regulation Of T Cell Proliferation
Cell Cycle Phase Transition
Positive Regulation Of Protein Kinase Activity
Bone Marrow Development
Stem Cell Development
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Positive Regulation Of Antigen Receptor-mediated Signaling Pathway
Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Regulation Of Cell Cycle
Positive Regulation Of Hematopoietic Stem Cell Migration
Positive Regulation Of Stem Cell Proliferation
Pathways
TCR signaling
Axon guidance
Semaphorin interactions
Other semaphorin interactions
Phosphorylation of CD3 and TCR zeta chains
Adaptive Immune System
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
20139978
)
Protein-protein Interactions
43 interactors:
ANP32A
CD1D
CD2
CD22
CD247
CD28
CD4
CD8A
CSNK2A1
CSNK2A2
CXCR4
DPP4
EZR
FCGR3A
FYN
GANAB
GRB2
IFNAR1
INSR
IRS1
ITGAL
JAK1
JAK2
JAK3
LCK
LCP2
LGALS1
LSM1
LYN
MBL2
PAEP
PPFIA1
PPFIBP2
PRKCSH
PTPN6
PTPRCAP
RASA1
RNF11
SEMA4D
SKAP1
TYK2
UHRF2
ZAP70
Entrez ID
5788
HPRD ID
01050
Ensembl ID
ENSG00000081237
Uniprot IDs
M9MML4
P08575
PDB IDs
1YGR
1YGU
Enriched GO Terms of Interacting Partners
?
Regulation Of Immune System Process
Regulation Of Immune Response
Positive Regulation Of Cell Activation
Immune Response
Immune System Process
Defense Response
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Innate Immune Response
Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell-cell Adhesion
Regulation Of Cell Adhesion
Peptidyl-tyrosine Autophosphorylation
Cell Activation
Positive Regulation Of Cell Adhesion
Regulation Of Cell Activation
Leukocyte Activation
Regulation Of Lymphocyte Activation
T Cell Costimulation
Leukocyte Cell-cell Adhesion
Positive Regulation Of Immune System Process
Homotypic Cell-cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Leukocyte Aggregation
Locomotion
Lymphocyte Activation
Single Organismal Cell-cell Adhesion
Cell Surface Receptor Signaling Pathway
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Antigen Receptor-mediated Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Signal Transduction
Response To Stress
Immune Response-regulating Signaling Pathway
Signal Transduction
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Cell Adhesion
Signaling
Response To Stimulus
Regulation Of Signal Transduction
Cell Communication
T Cell Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Intracellular Signal Transduction
Tagcloud
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abl
adaptor
bcr
cd45
chemistry
cief
cml
combines
crkl
describes
detect
example
focusing
isoelectric
limit
linking
lysate
nanocapillary
nanogram
nl
pg
protocol
ptyr207
quantities
reproducible
screen
throughput
tkis
uv