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PTPRC and RNF11
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
HPRD
(two hybrid)
PTPRC
RNF11
Gene Name
protein tyrosine phosphatase, receptor type, C
ring finger protein 11
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
External Side Of Plasma Membrane
Membrane
Membrane Raft
Extracellular Vesicular Exosome
Ubiquitin Ligase Complex
Nucleus
Early Endosome
Recycling Endosome
Extracellular Vesicular Exosome
Molecular Function
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Kinase Binding
DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Biological Process
Negative Regulation Of T Cell Mediated Cytotoxicity
Negative Regulation Of Cytokine-mediated Signaling Pathway
Hematopoietic Progenitor Cell Differentiation
Immunoglobulin Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Protein Dephosphorylation
Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration
Cell Surface Receptor Signaling Pathway
Axon Guidance
Dephosphorylation
T Cell Differentiation
Positive Regulation Of B Cell Proliferation
Peptidyl-tyrosine Dephosphorylation
B Cell Proliferation
Positive Regulation Of T Cell Proliferation
Cell Cycle Phase Transition
Positive Regulation Of Protein Kinase Activity
Bone Marrow Development
Stem Cell Development
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Positive Regulation Of Antigen Receptor-mediated Signaling Pathway
Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Regulation Of Cell Cycle
Positive Regulation Of Hematopoietic Stem Cell Migration
Positive Regulation Of Stem Cell Proliferation
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Pathways
TCR signaling
Axon guidance
Semaphorin interactions
Other semaphorin interactions
Phosphorylation of CD3 and TCR zeta chains
Adaptive Immune System
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
20139978
)
Ventricular conduction (
21076409
)
Protein-Protein Interactions
43 interactors:
ANP32A
CD1D
CD2
CD22
CD247
CD28
CD4
CD8A
CSNK2A1
CSNK2A2
CXCR4
DPP4
EZR
FCGR3A
FYN
GANAB
GRB2
IFNAR1
INSR
IRS1
ITGAL
JAK1
JAK2
JAK3
LCK
LCP2
LGALS1
LSM1
LYN
MBL2
PAEP
PPFIA1
PPFIBP2
PRKCSH
PTPN6
PTPRCAP
RASA1
RNF11
SEMA4D
SKAP1
TYK2
UHRF2
ZAP70
68 interactors:
AKT1
ANKRD13A
APP
ASCC2
AUP1
CALCOCO2
CBLB
CCDC127
DCUN1D1
EPN1
EPN2
EPN3
EPS15
ERCC6
GGA1
GGA2
GGA3
HERC1
HERC2
HUWE1
IKBKG
ITCH
MYO6
NEDD4
NEDD4L
OPTN
PDCD6IP
POLI
PTPRC
QARS
RABGEF1
RIPK1
RNF168
RNF216
RPS27A
SDCBP
SMURF1
SMURF2
SNRNP70
SPRTN
STAM2
STAMBP
STAMBPL1
TAX1BP1
TNFAIP3
TNIP1
TOM1L2
UBA52
UBAC1
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBQLN2
UBQLN4
USP5
WWP1
WWP2
ZFYVE16
ZFYVE9
ZNF350
Entrez ID
5788
26994
HPRD ID
01050
09955
Ensembl ID
ENSG00000081237
ENSG00000123091
Uniprot IDs
M9MML4
P08575
Q9Y3C5
PDB IDs
1YGR
1YGU
Enriched GO Terms of Interacting Partners
?
Regulation Of Immune System Process
Regulation Of Immune Response
Positive Regulation Of Cell Activation
Immune Response
Immune System Process
Defense Response
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Innate Immune Response
Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell-cell Adhesion
Regulation Of Cell Adhesion
Peptidyl-tyrosine Autophosphorylation
Cell Activation
Positive Regulation Of Cell Adhesion
Regulation Of Cell Activation
Leukocyte Activation
Regulation Of Lymphocyte Activation
T Cell Costimulation
Leukocyte Cell-cell Adhesion
Positive Regulation Of Immune System Process
Homotypic Cell-cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Leukocyte Aggregation
Locomotion
Lymphocyte Activation
Single Organismal Cell-cell Adhesion
Cell Surface Receptor Signaling Pathway
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Antigen Receptor-mediated Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Signal Transduction
Response To Stress
Immune Response-regulating Signaling Pathway
Signal Transduction
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Cell Adhesion
Signaling
Response To Stimulus
Regulation Of Signal Transduction
Cell Communication
T Cell Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Intracellular Signal Transduction
Protein Ubiquitination
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Cellular Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Positive Regulation Of Protein Catabolic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Proteolysis
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Positive Regulation Of Innate Immune Response
Regulation Of Protein Catabolic Process
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Cellular Protein Modification Process
Regulation Of Type I Interferon Production
Toll-like Receptor Signaling Pathway
Negative Regulation Of Signaling
Toll-like Receptor 4 Signaling Pathway
Protein K63-linked Ubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Innate Immune Response
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Cellular Protein Metabolic Process
Proteasomal Protein Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Type I Interferon Production
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Immune Response-regulating Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Intracellular Transport
Cellular Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Metabolic Process
Intracellular Protein Transport
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Innate Immune Response
Cellular Response To Stimulus
Tagcloud
?
abl
adaptor
bcr
cd45
chemistry
cief
cml
combines
crkl
describes
detect
example
focusing
isoelectric
limit
linking
lysate
nanocapillary
nanogram
nl
pg
protocol
ptyr207
quantities
reproducible
screen
throughput
tkis
uv
Tagcloud (Difference)
?
abl
adaptor
bcr
cd45
chemistry
cief
cml
combines
crkl
describes
detect
example
focusing
isoelectric
limit
linking
lysate
nanocapillary
nanogram
nl
pg
protocol
ptyr207
quantities
reproducible
screen
throughput
tkis
uv
Tagcloud (Intersection)
?