IRS1 and NTRK1

  • Number of citations of the paper that reports this interaction (PMID 11147812)
  • 5
  • Data Source:
  • HPRD (in vitro, two hybrid)

IRS1

NTRK1

Gene Name insulin receptor substrate 1 neurotrophic tyrosine kinase, receptor, type 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ 36 interactors: ABL1 ARHGAP32 CAV1 CRK DNAJA3 DYNLL1 FRS2 FRS3 GIPC1 GRB2 IRS1 IRS2 KIDINS220 MAPK3 MATK NEDD4 NEDD4L NGF NGFR NTF3 PIK3R1 PLCG1 PTPN1 PTPN11 RAP1A RASA1 RASGRF1 RUSC1 SH2B1 SH2B2 SHC1 SHC2 SHC3 SQSTM1 TRAF6 UBB
Entrez ID 3667 4914
HPRD ID 00943 01869
Ensembl ID ENSG00000169047 ENSG00000198400
Uniprot IDs P35568 P04629
PDB IDs 1IRS 1K3A 1QQG 2Z8C 1HE7 1SHC 1WWA 1WWW 2IFG 4AOJ 4F0I 4GT5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
aacr  accelerated  advancements  ago  approved  developments  discov  encodes  fda  fusions  harboring  next  oncd  oncogene  oncogenic  oncology  originally  precision  rationale  rearrangements  revisit  scientific  throughput  tpm3  transforming  trka  trkb  trkc 
Tagcloud (Difference) ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
aacr  accelerated  advancements  ago  approved  developments  discov  encodes  fda  fusions  harboring  next  oncd  oncogene  oncogenic  oncology  originally  precision  rationale  rearrangements  revisit  scientific  throughput  tpm3  transforming  trka  trkb  trkc 
Tagcloud (Intersection) ?