PBXIP1 and CCDC85B

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PBXIP1	CCDC85B
Description		PBX homeobox interacting protein 1	coiled-coil domain containing 85B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Cytoskeleton Microtubule	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Anchoring Junction
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding DNA-binding Transcription Factor Binding	Protein Binding Delta-catenin Binding
	Biological Process	Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of DNA-templated Transcription Cell Adhesion Gene Expression Cell Migration Extracellular Matrix Disassembly Hemopoiesis Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Articular Cartilage Development Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation	Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Acne (severe) ( 24927181) Asthma ( 31959851) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		27 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B DAXX DEF6 DPPA2 DSCR9 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	138 interacting genes: AGGF1 AKAP17A AKIRIN2 APEX2 AQP1 ATOSB BEX2 BEX3 BIRC5 C19orf25 C21orf91 C8orf48 CARD9 CATSPERT CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCNK CDK18 CDKN1A CENPP CEP70 CFAP53 CHCHD3 CHLSN COPS4 CWC25 DEPP1 DEUP1 DOK5 DTNB DUSP13B EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FNDC11 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 INO80B KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NIF3L1 NRIP1 NUP54 ODAD4 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RGS8 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SPATA46 SYT17 SYTL4 TASOR2 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF587 ZNF638 ZNF764 ZNF821
Entrez ID		57326	11007
HPRD ID		17823	16101
Ensembl ID		ENSG00000163346	ENSG00000175602
Uniprot IDs		B4E0K4 Q96AQ6	Q15834
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stress Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Metabolic Process Autophagy Regulation Of Primary Metabolic Process Regulation Of Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Metabolic Process Nucleus Chromatin Organization Cellular Response To Estrogen Stimulus Positive Regulation Of Proteolysis Regulation Of Macroautophagy Positive Regulation Of ERAD Pathway Autophagosome Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Metabolic Process Regulation Of ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into ER Membrane	Protein Binding Nucleus Nuclear Speck Zinc Ion Binding Spindle Pole Spindle Midzone Assembly Keratin Filament Chromatin Organization Regulation Of RNA Metabolic Process
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