PBXIP1 and ZMYND8

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PBXIP1	ZMYND8
Gene Name		pre-B-cell leukemia homeobox interacting protein 1	zinc finger, MYND-type containing 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding	RNA Polymerase II Transcription Corepressor Activity Protein Binding Zinc Ion Binding Repressing Transcription Factor Binding
	Biological Process	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3	9 interactors: ATN1 CSNK1E FHOD1 PBXIP1 PRKCB RERE USP7 ZBTB7A ZFYVE9
Entrez ID		57326	23613
HPRD ID		17823	10166
Ensembl ID		ENSG00000163346	ENSG00000101040
Uniprot IDs		B4E1J0 Q96AQ6	A6H8Y8 B7Z2A8 B7ZM62 F5H0X3 H7C0U2 J3KPU3 Q2HXV1 Q2HXV3 Q2HXV5 Q569J9 Q9ULU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade	Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Histone H3-T6 Phosphorylation Protein Import Into Nucleus Nuclear Import Chromatin Modification Protein Import Protein Localization To Nucleus Chromatin Organization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Maintenance Of DNA Methylation Heterocycle Metabolic Process SMAD Protein Import Into Nucleus Positive Regulation Of B Cell Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Localization Cellular Nitrogen Compound Metabolic Process Nucleocytoplasmic Transport Nuclear Transport SMAD Protein Complex Assembly Maintenance Of Cell Polarity Toxin Metabolic Process Chromosome Organization Negative Regulation Of Glucose Transport Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Organelle Transcription, DNA-templated Histone Deubiquitination Lipoprotein Transport NLS-bearing Protein Import Into Nucleus Negative Regulation Of Signaling RNA Biosynthetic Process Regulation Of Protein Catabolic Process Histone Modification
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