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PBXIP1 and PCBD2
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
PBXIP1
PCBD2
Gene Name
pre-B-cell leukemia homeobox interacting protein 1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Microtubule
Cellular_component
Nucleus
Mitochondrion
Molecular Function
Transcription Corepressor Activity
Protein Binding
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Biological Process
Multicellular Organismal Development
Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Tetrahydrobiopterin Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Bulimia nervosa (
23568457
)
Colorectal cancer (
23263487
)
Height (
18391951
)
Protein-Protein Interactions
19 interactors:
BRPF1
CCDC53
CCDC85B
CCNC
DAXX
DEF6
DPPA2
GMCL1
GRB2
MDFI
MORF4L1
PCBD2
PRKAA2
SGTA
TSNAX
UBQLN1
UBQLN4
ZMYND8
ZZZ3
31 interactors:
AATF
APP
ASCC2
BRF1
C1D
CDC5L
CENPK
CHAF1A
GTF2E1
HES4
IRF2BP1
KCNIP3
MAGEA11
MED21
MED30
MED4
MED7
MET
PBXIP1
PCBD1
PHF14
PML
RUNX1T1
SNW1
SSX3
SSX5
STAT3
TAL2
TGIF2LY
XBP1
ZZZ3
Entrez ID
57326
84105
HPRD ID
17823
17824
Ensembl ID
ENSG00000163346
Uniprot IDs
B4E1J0
Q96AQ6
Q9H0N5
PDB IDs
4C45
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Gene Expression
Chromatin Organization
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Activation Of JUN Kinase Activity
Cellular Nitrogen Compound Metabolic Process
Cellular Response To Stress
Cellular Macromolecule Biosynthetic Process
Chromosome Organization
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Chromatin Modification
Positive Regulation Of JUN Kinase Activity
Biosynthetic Process
Regulation Of JUN Kinase Activity
JNK Cascade
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Histone Modification
Embryonic Placenta Development
Histone Acetylation
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of JNK Cascade
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Protein Heterooligomerization
Positive Regulation Of Stress-activated MAPK Cascade
Protein Acetylation
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Protein Metabolic Process
Activation Of MAPK Activity
Insulin Receptor Signaling Pathway
Carnitine Shuttle
Tetrahydrobiopterin Biosynthetic Process
Regulation Of JNK Cascade
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Apoptotic Process
Negative Regulation Of Gene Expression
Programmed Cell Death
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Cell Death
Death
Stem Cell Maintenance
Transcription From RNA Polymerase II Promoter
Cell Differentiation
Positive Regulation Of Histone Modification
Negative Regulation Of Cell Differentiation
Stem Cell Development
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Differentiation
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Tagcloud (Intersection)
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