PBXIP1 and BRPF1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PBXIP1	BRPF1
Gene Name		pre-B-cell leukemia homeobox interacting protein 1	bromodomain and PHD finger containing, 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule	Nucleus Nucleoplasm Cytoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Chromatin Organization Transcription, DNA-templated Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3	4 interactors: GTF2H1 HIST2H3C MEAF6 PBXIP1
Entrez ID		57326	7862
HPRD ID		17823	03875
Ensembl ID		ENSG00000163346	ENSG00000156983
Uniprot IDs		B4E1J0 Q96AQ6	P55201
PDB IDs			2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade	Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Histone H3-K14 Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Histone H4-K12 Acetylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation On Cytosine Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H2A Acetylation Chromatin Silencing At RDNA Nucleotide-excision Repair, DNA Damage Removal Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Chromatin Silencing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Histone H3 Acetylation Positive Regulation Of Viral Transcription Histone H4 Acetylation Regulation Of Metabolic Process DNA Methylation Transcription Elongation From RNA Polymerase II Promoter Gene Expression DNA Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process DNA-templated Transcription, Termination Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Elongation DNA Modification Nucleotide-excision Repair Gene Silencing Negative Regulation Of Biosynthetic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation
Tagcloud ?			acetylates acetyllysine bonding bromodomain calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones ing5 monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Difference) ?			acetylates acetyllysine bonding bromodomain calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones ing5 monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Intersection) ?