PBXIP1 and PPTC7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PBXIP1	PPTC7
Description		PBX homeobox interacting protein 1	protein phosphatase targeting COQ7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Cytoskeleton Microtubule	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding DNA-binding Transcription Factor Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of DNA-templated Transcription Cell Adhesion Gene Expression Cell Migration Extracellular Matrix Disassembly Hemopoiesis Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Articular Cartilage Development Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation	Mitophagy Regulation Of Ubiquinone Biosynthetic Process Negative Regulation Of Mitophagy Positive Regulation Of Ubiquinone Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		27 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B DAXX DEF6 DPPA2 DSCR9 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	4 interacting genes: BCL6 BNIP3 PBXIP1 ZDHHC17
Entrez ID		57326	160760
HPRD ID		17823	18141
Ensembl ID		ENSG00000163346	ENSG00000196850
Uniprot IDs		B4E0K4 Q96AQ6	Q8NI37
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stress Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Metabolic Process Autophagy Regulation Of Primary Metabolic Process Regulation Of Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Metabolic Process Nucleus Chromatin Organization Cellular Response To Estrogen Stimulus Positive Regulation Of Proteolysis Regulation Of Macroautophagy Positive Regulation Of ERAD Pathway Autophagosome Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Metabolic Process Regulation Of ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into ER Membrane	Negative Regulation Of Isotype Switching To IgE Isotypes Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Mast Cell Cytokine Production Hemopoiesis Isotype Switching To IgE Isotypes Negative Regulation Of Plasma Cell Differentiation DNA-binding Transcription Factor Binding Intronic Transcription Regulatory Region Sequence-specific DNA Binding Cellular Response To Cobalt Ion Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Mitochondrion Autophagosome Adaptor Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Gene Expression Involved In Extracellular Matrix Organization Negative Regulation Of T-helper 2 Cell Differentiation Negative Regulation Of Isotype Switching Pyramidal Neuron Differentiation Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Endoplasmic Reticulum-autophagosome Adaptor Activity Autophagic Cell Death Protein-cysteine S-myristoyltransferase Activity Articular Cartilage Development Plasma Cell Differentiation Negative Regulation Of B Cell Differentiation Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein-cysteine S-stearoyltransferase Activity Paraspeckles T-helper 2 Cell Differentiation Type 2 Immune Response Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Immunoglobulin Production Negative Regulation Of B Cell Apoptotic Process Negative Regulation Of DNA-templated DNA Replication Negative Regulation Of Type 2 Immune Response Germinal Center Formation Regulation Of Memory T Cell Differentiation Regulation Of Germinal Center Formation Regulation Of Programmed Cell Death Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Muscle Cell Apoptotic Process Mitochondrial Protein Catabolic Process Response To Oxygen-glucose Deprivation Regulation Of Mitochondrial Fusion Response To Cobalt Ion Striated Muscle Cell Apoptotic Process Negative Regulation Of Membrane Potential Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
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