PBXIP1 and DPPA2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		PBXIP1	DPPA2
Gene Name		pre-B-cell leukemia homeobox interacting protein 1	developmental pluripotency associated 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule	Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding	Chromatin Binding
	Biological Process	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Regulation Of Histone Methylation Lung-associated Mesenchyme Development Positive Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Corneal astigmatism ( 23761726)
Protein-Protein Interactions		19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3	16 interactors: AP2M1 DPPA4 DVL2 DVL3 FXR2 MCM10 MOAP1 PBXIP1 PLOD3 SDCBP2 SETD5 SPOP U2AF2 VTA1 ZCCHC10 ZNF250
Entrez ID		57326	151871
HPRD ID		17823	13248
Ensembl ID		ENSG00000163346	ENSG00000163530
Uniprot IDs		B4E1J0 Q96AQ6	Q7Z7J5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade	Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Cochlea Morphogenesis Non-canonical Wnt Signaling Pathway Cochlea Development Outflow Tract Morphogenesis Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Intracellular Transport Canonical Wnt Signaling Pathway Cellular Localization Inner Ear Morphogenesis Convergent Extension Involved In Neural Plate Elongation Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Embryonic Development Protein Insertion Into Mitochondrial Membrane Basement Membrane Assembly Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of JNK Cascade Ear Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Non-canonical Wnt Signaling Pathway Via MAPK Cascade Convergent Extension Involved In Organogenesis Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Protein Localization Positive Regulation Of Wnt Signaling Pathway Regulation Of JNK Cascade Establishment Of Localization In Cell Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Neural Plate Morphogenesis Regulation Of Organ Morphogenesis Regulation Of Stress-activated MAPK Cascade Inner Ear Development Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Neural Tube Development Mitochondrial Outer Membrane Permeabilization Positive Regulation Of MAP Kinase Activity Endothelial Cell Morphogenesis Tube Development Heart Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Ear Development
Tagcloud ?			butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Difference) ?			butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Intersection) ?