PBXIP1 and DEF6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PBXIP1	DEF6
Gene Name		pre-B-cell leukemia homeobox interacting protein 1	differentially expressed in FDCP 6 homolog (mouse)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding
	Biological Process	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Height ( 18391951)
Protein-Protein Interactions		19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3	15 interactors: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70
Entrez ID		57326	50619
HPRD ID		17823	10869
Ensembl ID		ENSG00000163346	ENSG00000023892
Uniprot IDs		B4E1J0 Q96AQ6	Q9H4E7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade	Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Regulation Of Signal Transduction Axon Guidance Regulation Of Signaling Regulation Of Intracellular Signal Transduction Regulation Of Cell Morphogenesis Locomotion Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Projection Organization Response To External Stimulus Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Immune System Process Positive Regulation Of Cell Projection Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Axon Development Regulation Of Cell Projection Assembly Cell Morphogenesis Involved In Neuron Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cellular Component Biogenesis Chemotaxis Regulation Of Cell Adhesion Regulation Of Cell Differentiation Neuron Projection Morphogenesis Positive Regulation Of Immune Response Peptidyl-tyrosine Autophosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Signal Transduction Cell Differentiation Innate Immune Response Regulation Of Cell-substrate Adhesion Neuron Projection Development Response To Stress Regulation Of Immune System Process Regulation Of Lipid Kinase Activity Cell Migration
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