KRTAP9-2 and RCHY1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP9-2	RCHY1
Gene Name		keratin associated protein 9-2	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function		P53 Binding Ubiquitin-protein Transferase Activity Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity
	Biological Process		Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions		54 interactors: ADAMTSL4 AQP1 ARFGAP1 C19orf66 CATSPER1 CCDC28A CHRD COL8A1 CREB5 DOCK2 FAM76B GATA1 GLRX3 GNE HOXA1 JOSD1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-4 LCE1B LCE2A LCE3E LCE4A LNX1 MAPKBP1 MEOX2 NOTCH2NL NUFIP2 OTX1 PDE9A PLSCR1 PRKAB2 PTPMT1 RCHY1 RNF31 SMCP SPATA8 SPRY2 SUMO1P1 TMSB10 WDYHV1 ZDHHC17	61 interactors: ADAMTSL4 AIG1 AOX1 AR ARF4 ATN1 BIRC3 C19orf80 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DCUN1D5 F7 FADS6 GFI1B GORAB HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NL PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBE2D2 UBE2D4 WDR74 ZNF160
Entrez ID		83899	25898
HPRD ID		13949	07607
Ensembl ID		ENSG00000239886	ENSG00000163743
Uniprot IDs		Q9BYQ4	C7E542 E7EMC8 E7ETW5 J3KPI0 Q96PM5
PDB IDs			2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?		Keratinization Keratinocyte Differentiation Epithelium Development Tissue Development Organ Development Epidermis Development Epidermal Cell Differentiation Developmental Process Skin Development Multicellular Organismal Development Inner Ear Morphogenesis Cell Differentiation Ear Morphogenesis Embryo Development System Development Sensory Organ Development BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Localization Within Membrane Ammonium Transmembrane Transport Anatomical Structure Development Embryonic Morphogenesis Establishment Or Maintenance Of Cell Polarity Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Myeloid Dendritic Cell Activation Involved In Immune Response Facial Nucleus Development Basophil Differentiation Carbon Dioxide Transmembrane Transport Corticotropin Secretion CD40 Signaling Pathway Eosinophil Fate Commitment N-acetylglucosamine Biosynthetic Process Establishment Or Maintenance Of Actin Cytoskeleton Polarity Sperm Motility Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell-cell Recognition Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Eosinophil Differentiation Metanephric Proximal Convoluted Tubule Development Rhombomere 4 Development Nitric Oxide Transport Semicircular Canal Formation Transcriptional Activation By Promoter-enhancer Looping	Signal Transduction In Response To DNA Damage DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic DNA Damage Checkpoint DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Signal Transduction By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Protein Metabolic Process Response To Stress Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Mitotic Cell Cycle Checkpoint Response To Gamma Radiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Ionizing Radiation Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Cellular Response To Stress Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Cell Cycle Arrest Mitotic Cell Cycle Process Cellular Response To DNA Damage Stimulus Cell Cycle Process Positive Regulation Of Metabolic Process Cell Death Death Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process Response To Abiotic Stimulus Positive Regulation Of Blood Vessel Remodeling Negative Regulation Of Apoptotic Process Regulation Of Body Fluid Levels Negative Regulation Of Programmed Cell Death
Tagcloud ?			20s alters animal conserved correlatively crucial degradation display e3 establish handful homeodomain hox hoxa2 interacts ligase modes multitude pirh2 promotes proteasomal proteasome regulators reports reveal stabilization subunits ubiquitin ubiquitination
Tagcloud (Difference) ?			20s alters animal conserved correlatively crucial degradation display e3 establish handful homeodomain hox hoxa2 interacts ligase modes multitude pirh2 promotes proteasomal proteasome regulators reports reveal stabilization subunits ubiquitin ubiquitination
Tagcloud (Intersection) ?