KRTAP9-2 and P2RY6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP9-2	P2RY6
Description		keratin associated protein 9-2	pyrimidinergic receptor P2Y6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding	G Protein-coupled ADP Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Purinergic Nucleotide Receptor Activity G Protein-coupled UDP Receptor Activity G Protein-coupled UTP Receptor Activity
	Biological Process		Phagocytosis Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Transepithelial Chloride Transport Positive Regulation Of Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Prostaglandin E Stimulus Cellular Response To Purine-containing Compound Cellular Response To Oxygen-containing Compound Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Cellular Response To Pyrimidine Ribonucleotide
Pathways		Keratinization	G alpha (q) signalling events P2Y receptors
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		146 interacting genes: ADAM12 ADAMTSL4 AGXT AQP1 ARFGAP1 ATG9A AXIN2 C22orf39 CARD10 CATSPER1 CCDC28A CERK CHRD CNNM3 COL8A1 CRCT1 CREB5 CTRC CYP21A2 CYSRT1 DMRT3 DOCK2 FAM76B FBXO34 GATA1 GEMIN4 GLRX3 GNE GNG13 GUCD1 HAPLN2 HOXA1 ITGB4 JOSD1 KLHL38 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MGAT5B NBPF19 NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 P2RY6 P3H3 PDE9A PHLDA1 PIGS PLLP PLSCR1 POTEB3 POU4F2 PRKAB2 PRKAG1 PTPMT1 RCHY1 RNF31 RNF8 SDC3 SHFL SLC13A5 SLC39A7 SMCP SPATA3 SPATA8 SPRY1 SPRY2 SUMO1P1 TFAP2D TMEM190 TMSB10 TRIM54 TSPAN4 TYRO3 VASN VGLL3 ZDHHC1 ZDHHC17 ZNF20 ZNF575 ZNF696	16 interacting genes: CFTR HOXA1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP5-9 KRTAP9-2 MCFD2 NBPF19 NOTCH2NLA PLSCR1
Entrez ID		83899	5031
HPRD ID		13949	03906
Ensembl ID		ENSG00000239886	ENSG00000171631
Uniprot IDs		A0A140TA58 Q9BYQ4	Q15077
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding Hair Cycle Identical Protein Binding Regulation Of Neurotrophin TRK Receptor Signaling Pathway	Intermediate Filament Keratin Filament
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