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KRTAP9-2 and DOCK2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP9-2
DOCK2
Gene Name
keratin associated protein 9-2
dedicator of cytokinesis 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Cytosol
Cytoskeleton
Endomembrane System
Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Rac GTPase Activator Activity
Rac Guanyl-nucleotide Exchange Factor Activity
T Cell Receptor Binding
Biological Process
Membrane Raft Polarization
Establishment Of T Cell Polarity
Immunological Synapse Formation
Myeloid Dendritic Cell Activation Involved In Immune Response
Chemotaxis
Small GTPase Mediated Signal Transduction
Viral Process
Actin Cytoskeleton Organization
Positive Regulation Of Rac GTPase Activity
Macropinocytosis
Positive Thymic T Cell Selection
Negative Thymic T Cell Selection
Alpha-beta T Cell Proliferation
Regulation Of Defense Response To Virus By Virus
Positive Regulation Of Phagocytosis
Pathways
HIV Infection
Host Interactions of HIV factors
The role of Nef in HIV-1 replication and disease pathogenesis
Factors involved in megakaryocyte development and platelet production
Nef and signal transduction
Drugs
Diseases
GWAS
Protein quantitative trait loci (
18464913
)
Protein-Protein Interactions
54 interactors:
ADAMTSL4
AQP1
ARFGAP1
C19orf66
CATSPER1
CCDC28A
CHRD
COL8A1
CREB5
DOCK2
FAM76B
GATA1
GLRX3
GNE
HOXA1
JOSD1
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-4
LCE1B
LCE2A
LCE3E
LCE4A
LNX1
MAPKBP1
MEOX2
NOTCH2NL
NUFIP2
OTX1
PDE9A
PLSCR1
PRKAB2
PTPMT1
RCHY1
RNF31
SMCP
SPATA8
SPRY2
SUMO1P1
TMSB10
WDYHV1
ZDHHC17
25 interactors:
CALCOCO2
CCNDBP1
CD247
CRKL
HNRNPK
KHDRBS1
KHDRBS2
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
MDFI
MTUS2
NOTCH2NL
PAK2
PLSCR1
RAC1
RAC2
TRIM23
VAV1
Entrez ID
83899
1794
HPRD ID
13949
09121
Ensembl ID
ENSG00000239886
ENSG00000134516
Uniprot IDs
Q9BYQ4
Q5XG91
Q92608
PDB IDs
2RQR
2YIN
3A98
3B13
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epithelium Development
Tissue Development
Organ Development
Epidermis Development
Epidermal Cell Differentiation
Developmental Process
Skin Development
Multicellular Organismal Development
Inner Ear Morphogenesis
Cell Differentiation
Ear Morphogenesis
Embryo Development
System Development
Sensory Organ Development
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Localization Within Membrane
Ammonium Transmembrane Transport
Anatomical Structure Development
Embryonic Morphogenesis
Establishment Or Maintenance Of Cell Polarity
Inner Ear Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Myeloid Dendritic Cell Activation Involved In Immune Response
Facial Nucleus Development
Basophil Differentiation
Carbon Dioxide Transmembrane Transport
Corticotropin Secretion
CD40 Signaling Pathway
Eosinophil Fate Commitment
N-acetylglucosamine Biosynthetic Process
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Sperm Motility
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cell-cell Recognition
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Eosinophil Differentiation
Metanephric Proximal Convoluted Tubule Development
Rhombomere 4 Development
Nitric Oxide Transport
Semicircular Canal Formation
Transcriptional Activation By Promoter-enhancer Looping
T Cell Costimulation
Regulation Of Defense Response To Virus By Virus
Viral Process
Platelet Activation
Positive Regulation Of T Cell Activation
Regulation Of Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Immune System Process
Positive Regulation Of Cell-cell Adhesion
Regulation Of Hydrogen Peroxide Metabolic Process
Regulation Of Defense Response To Virus
Fc Receptor Signaling Pathway
Regulation Of Respiratory Burst
Positive Regulation Of Catalytic Activity
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Lamellipodium Assembly
Regulation Of T Cell Activation
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Activation
Regulation Of Cell Adhesion
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Immune Response
Positive Regulation Of Lamellipodium Organization
Signal Transduction
Regulation Of Cell-cell Adhesion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Neutrophil Chemotaxis
Regulation Of Lamellipodium Assembly
Positive Regulation Of Metabolic Process
Regulation Of Lymphocyte Activation
Response To Stress
Regulation Of Immune System Process
Positive Regulation Of Granulocyte Chemotaxis
Innate Immune Response
Blood Coagulation
Defense Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Hemostasis
Signaling
Response To Stimulus
Regulation Of Neutrophil Chemotaxis
Regulation Of Signal Transduction
Regulation Of Neutrophil Migration
Cell Communication
Regulation Of Immune Response
Tagcloud
?
abolish
atypical
beta2
chemotaxis
cpypp
dock5
fmlf
gef
gefs
gtpase
guanine
integrin
invading
kill
lacking
leukocytes
migrate
motile
net
nets
neutrophil
neutrophils
normally
participate
pathogens
pma
rac
ros
Tagcloud (Difference)
?
abolish
atypical
beta2
chemotaxis
cpypp
dock5
fmlf
gef
gefs
gtpase
guanine
integrin
invading
kill
lacking
leukocytes
migrate
motile
net
nets
neutrophil
neutrophils
normally
participate
pathogens
pma
rac
ros
Tagcloud (Intersection)
?