KRTAP9-2 and PLSCR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP9-2	PLSCR1
Description		keratin associated protein 9-2	phospholipid scramblase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Magnesium Ion Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Virus Receptor Activity DNA Binding Nuclease Activity Epidermal Growth Factor Receptor Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Hydrolase Activity SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding Lead Ion Binding CD4 Receptor Binding Mercury Ion Binding
	Biological Process		Phosphatidylserine Biosynthetic Process Lipid Transport Apoptotic Process Acute-phase Response Response To Lead Ion Positive Regulation Of Gene Expression Plasma Membrane Phospholipid Scrambling Platelet Activation Regulation Of Mast Cell Activation Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Symbiont Entry Into Host Cell Negative Regulation Of Phagocytosis Defense Response To Virus Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Chromosome Separation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Pathways		Keratinization
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		146 interacting genes: ADAM12 ADAMTSL4 AGXT AQP1 ARFGAP1 ATG9A AXIN2 C22orf39 CARD10 CATSPER1 CCDC28A CERK CHRD CNNM3 COL8A1 CRCT1 CREB5 CTRC CYP21A2 CYSRT1 DMRT3 DOCK2 FAM76B FBXO34 GATA1 GEMIN4 GLRX3 GNE GNG13 GUCD1 HAPLN2 HOXA1 ITGB4 JOSD1 KLHL38 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MGAT5B NBPF19 NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 P2RY6 P3H3 PDE9A PHLDA1 PIGS PLLP PLSCR1 POTEB3 POU4F2 PRKAB2 PRKAG1 PTPMT1 RCHY1 RNF31 RNF8 SDC3 SHFL SLC13A5 SLC39A7 SMCP SPATA3 SPATA8 SPRY1 SPRY2 SUMO1P1 TFAP2D TMEM190 TMSB10 TRIM54 TSPAN4 TYRO3 VASN VGLL3 ZDHHC1 ZDHHC17 ZNF20 ZNF575 ZNF696	132 interacting genes: ABL1 ADAMTSL4 ADCY7 ANXA11 APP ARNT2 ATG12 ATN1 BACE1 BCL6B C10orf62 CATSPER1 CCDC33 CCER1 CDC42EP1 CHRD CNTFR CPSF6 CRK CRKL CRY1 CTBP1-DT CTSZ DAZAP2 DDIAS DEF6 DEPP1 DHRS1 DLK2 DMRT3 DOCK2 DTX2 EFEMP2 EGFR ENKD1 EP300 ESR2 EWSR1 EXD3 FAM107A FBLN1 FBXL18 FRAT1 FRS3 GDPD5 GLRX3 GNAI2 GPRIN2 HEY2 HOXA1 HOXA9 HOXB6 HRG ILF3 INTS11 IP6K2 IQCN KIF1A KRTAP10-11 KRTAP10-3 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 LASP1 LCE2D LCE3C LCE4A LGALS9C LINC00663 LINC01547 LONRF1 MAPK6 MDK MED15 MGAT5B MVP NECAP2 NEU4 NOC4L NPDC1 NR0B2 NTN4 OGDH P2RY6 PCED1A PGLS PHLDA1 PITX1 PKD2 PLSCR3 PLSCR4 PML PPDPF PRKCD PRR13 RAMAC RASD1 RBL1 RERE RGS3 RXRB SCNM1 SF1 SHC1 SLC25A6 SLC35A2 SLPI SMARCC1 SMCP SPATA8 SPG7 SPRY2 SRC STK16 TFG THBS1 TRAF4 TRIM42 VASP VPS37C VSIR YIPF3 ZBTB16 ZNF417 ZNF581 ZNF587 ZNF638 ZNF688 ZNF764
Entrez ID		83899	5359
HPRD ID		13949	08855
Ensembl ID		ENSG00000239886	ENSG00000188313
Uniprot IDs		A0A140TA58 Q9BYQ4	C9J7K9 O15162
PDB IDs			1Y2A
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding Hair Cycle Identical Protein Binding Regulation Of Neurotrophin TRK Receptor Signaling Pathway	Enzyme Binding Ephrin Receptor Binding Protein Binding Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Cell-substrate Adhesion Cellular Response To Transforming Growth Factor Beta Stimulus Keratin Filament Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Transforming Growth Factor Beta Intermediate Filament Response To Growth Factor Regulation Of Cell Adhesion Positive Regulation Of MAPK Cascade Helper T Cell Diapedesis Shc-EGFR Complex Positive Regulation Of Cell-substrate Adhesion Regulation Of Superoxide Metabolic Process Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Adhesion Response To Lipid Hair Cycle Apoptotic Process Regulation Of Focal Adhesion Assembly Regulation Of MAPK Cascade Cerebellar Neuron Development Regulation Of Apoptotic Process Protein Tyrosine Kinase Activator Activity Cellular Response To Lipid Morphogenesis Of A Branching Structure ERBB Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of Cell-substrate Junction Organization Gland Development Regulation Of RNA Biosynthetic Process Programmed Cell Death Cell Death Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Non-membrane Spanning Protein Tyrosine Kinase Activity Epidermal Growth Factor Binding System Development Regulation Of Cell Population Proliferation Cellular Response To Oxygen-containing Compound Positive Regulation Of Cell Migration Regulation Of Programmed Cell Death Regulation Of Cell-matrix Adhesion Positive Regulation Of Superoxide Anion Generation Central Nervous System Neuron Development
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