KRT40 and HBA2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT40	HBA2
Gene Name		keratin 40, type I	hemoglobin, alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament	Extracellular Region Cytosol Hemoglobin Complex Membrane Cytosolic Small Ribosomal Subunit Haptoglobin-hemoglobin Complex Extracellular Vesicular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Structural Molecule Activity	Peroxidase Activity Oxygen Transporter Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding
	Biological Process		Receptor-mediated Endocytosis Positive Regulation Of Cell Death Oxygen Transport Bicarbonate Transport Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Small Molecule Metabolic Process Protein Heterooligomerization Oxidation-reduction Process
Pathways			O2/CO2 exchange in erythrocytes Scavenging of heme from plasma Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide
Drugs			Mefloquine Iron Dextran 4-Carboxycinnamic Acid 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine SEBACIC ACID 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID 2,6-DICARBOXYNAPHTHALENE 2-{4-[(3,5-DIMETHYLANILINO)-CARBONYL-METHYL]-PHENOXY}-2-METHYLPROPIONIC ACID 1,3,5-BENZENETRICARBOXYLIC ACID
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions		313 interactors: ADAMTSL3 AEN AES AKAP17A ALDH3B1 ALS2CR11 ANKRD36BP1 AP1M1 AQP1 AQP5 ARID5A ARMC7 ARSI ASMTL ATPAF2 AVPI1 BAHD1 BARD1 BCAS2 BEX2 BMS1P5 BYSL C10orf62 C11orf87 C14orf105 C19orf57 C19orf66 C19orf73 C1orf109 C1orf216 C20orf195 C22orf46 C5orf60 C6orf165 C6orf226 C8orf48 CA6 CARD9 CATIP CBX8 CCDC112 CCDC120 CCDC146 CCDC185 CCDC26 CCDC93 CCER1 CCHCR1 CCNG1 CD33 CDC20B CDK18 CDK5R1 CELA2B CEP57 CEP57L1 CHCHD2 CHCHD3 CHIC2 CLEC18A CNTF COL8A1 COMT COX5A CREB5 CTSZ CWF19L2 CYCS CYTH4 DAAM2 DCDC2B DCX DDX6 DLGAP2 DMRT3 DOCK2 DOCK8 DTNB EIF4E2 EXOC3-AS1 FAM107A FAM124B FAM214A FAM27E3 FAM64A FAM71C FAM74A4 FAM90A1 FARS2 FASLG FBF1 FBXL18 FBXO34 FBXW5 FKBP1B FOXB1 FRG1 GATA2 GATAD2A GEM GFOD1 GGN GLIDR GNAI2 GNG5 GOLGA6L2 GPATCH2L GTF3C5 GUCD1 HAUS1 HBA2 HBZ HCK HDAC4 HGS HOXA1 HSPA12B HSPD1 ING5 INPP5D IQUB ISCU ITGB5 JOSD1 KAT5 KCTD9 KIFC3 KLHL38 KPNA2 KRT2 KRT20 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LAGE3 LCE3E LENG1 LIMS2 LIN37 LINC00636 LINC01588 LMF2 LMO1 LMO2 LMO4 LOC149950 LRCH4 MAB21L2 MAGOHB MAPKBP1 MARK4 MED8 METTL17 MFAP1 MOB3C MOS MRPL11 MTA1 MXI1 NAB2 NAPRT NDEL1 NEK6 NFKBID NINJ1 NPBWR2 NPPB NR1D2 NXF1 OPCML OTUB2 PDLIM5 PGLS PHF21A PIGS PIN1 PKD2 POLDIP3 POLL POM121L8P POP5 PPP1R18 PRAM1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMC5 PTGER3 PTPMT1 PXMP2 QPRT RAB3IL1 RAB3IP RAC1 RASSF5 RBM41 RCOR3 RECK RNF213 RPL11 RSPH14 RTP5 RWDD2B SCOC SEMA4C SETD5 SH2D4A SHC3 SIRPA SLC25A10 SLIRP SLU7 SMARCE1 SMCO4 SNAI1 SNHG11 SNRPB SNW1 SPATA24 SPEF1 SPG7 SRSF2 SSX2 SSX2IP SYT6 TAPBPL TBC1D16 TBC1D22B TCEA2 TCEB3 TCHP THAP7 TIE1 TMEM231 TMEM241 TMSB4X TNIP3 TNNT1 TRAF4 TRIM42 TROAP TRPV6 TSC22D4 TSGA10IP TSHZ3 TTC23 TTC25 TTLL10 TXLNA TXN2 TXNDC5 TYK2 TYRO3 UACA UBASH3A UCMA USHBP1 USP2 USP21 UTP14C UTP23 UXT WDR25 WT1 WT1-AS ZBTB16 ZBTB24 ZBTB38 ZC2HC1C ZFHX3 ZFP2 ZFP69B ZFYVE21 ZFYVE26 ZGPAT ZMAT2 ZNF101 ZNF124 ZNF138 ZNF165 ZNF20 ZNF202 ZNF230 ZNF250 ZNF26 ZNF266 ZNF286A ZNF317 ZNF329 ZNF337 ZNF417 ZNF439 ZNF446 ZNF488 ZNF490 ZNF564 ZNF569 ZNF581 ZNF587 ZNF625 ZNF655 ZNF697 ZNF702P ZNF792 ZNF844 ZNRF2P1 ZSCAN21	8 interactors: AHSP CCDC57 CPM HBB HBE1 KRT40 SPP1 UCHL5
Entrez ID		125115	3040
HPRD ID		08304	00785
Ensembl ID		ENSG00000204889	ENSG00000188536
Uniprot IDs		Q6A162	D1MGQ2 P69905
PDB IDs			1A00 1A01 1A0U 1A0Z 1A3N 1A3O 1A9W 1ABW 1ABY 1AJ9 1B86 1BAB 1BBB 1BIJ 1BUW 1BZ0 1BZ1 1BZZ 1C7B 1C7C 1C7D 1CLS 1CMY 1COH 1DKE 1DXT 1DXU 1DXV 1FDH 1FN3 1G9V 1GBU 1GBV 1GLI 1GZX 1HAB 1HAC 1HBA 1HBB 1HBS 1HCO 1HDB 1HGA 1HGB 1HGC 1HHO 1IRD 1J3Y 1J3Z 1J40 1J41 1J7S 1J7W 1J7Y 1JY7 1K0Y 1K1K 1KD2 1LFL 1LFQ 1LFT 1LFV 1LFY 1LFZ 1LJW 1M9P 1MKO 1NEJ 1NIH 1NQP 1O1I 1O1J 1O1K 1O1L 1O1M 1O1N 1O1O 1O1P 1QI8 1QSH 1QSI 1QXD 1QXE 1R1X 1R1Y 1RPS 1RQ3 1RQ4 1RQA 1RVW 1SDK 1SDL 1SHR 1SI4 1THB 1UIW 1VWT 1XXT 1XY0 1XYE 1XZ2 1XZ4 1XZ5 1XZ7 1XZU 1XZV 1Y01 1Y09 1Y0A 1Y0C 1Y0D 1Y0T 1Y0W 1Y22 1Y2Z 1Y31 1Y35 1Y45 1Y46 1Y4B 1Y4F 1Y4G 1Y4P 1Y4Q 1Y4R 1Y4V 1Y5F 1Y5J 1Y5K 1Y7C 1Y7D 1Y7G 1Y7Z 1Y83 1Y85 1Y8W 1YDZ 1YE0 1YE1 1YE2 1YEN 1YEO 1YEQ 1YEU 1YEV 1YFF 1YG5 1YGD 1YGF 1YH9 1YHE 1YHR 1YIE 1YIH 1YVQ 1YVT 1YZI 1Z8U 2D5Z 2D60 2DN1 2DN2 2DN3 2DXM 2H35 2HBC 2HBD 2HBE 2HBF 2HBS 2HCO 2HHB 2HHD 2HHE 2M6Z 2W6V 2W72 2YRS 3B75 3D17 3D7O 3DUT 3HHB 3HXN 3IA3 3IC0 3IC2 3KMF 3NL7 3NMM 3ODQ 3ONZ 3OO4 3OO5 3OVU 3P5Q 3QJB 3QJC 3QJD 3QJE 3R5I 3S48 3S65 3S66 3SZK 3WCP 4FC3 4HHB 4L7Y 4MQC 4MQG 4MQH 4MQI 4MQJ 6HBW
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Defense Response To Virus By Virus Regulation Of Cell Death Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Apoptotic Process Bicarbonate Transport Cell Death Death Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Microtubule Organizing Center Organization Positive Regulation Of Cellular Protein Metabolic Process Intermediate Filament-based Process Organelle Organization Multicellular Organismal Development	Oxygen Transport Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Heterooligomerization Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Nitric Oxide Transport
Tagcloud ?			accurate anaemia analysed arab child children deficiency dehydrogenase females ferritin g6pd haemoglobin index iran iron islamic males migrating ng nomad phosphate prevalence republic schoolchildren serum southern thalassaemia trait
Tagcloud (Difference) ?			accurate anaemia analysed arab child children deficiency dehydrogenase females ferritin g6pd haemoglobin index iran iron islamic males migrating ng nomad phosphate prevalence republic schoolchildren serum southern thalassaemia trait
Tagcloud (Intersection) ?