PEF1 and EWSR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PEF1	EWSR1
Description		penta-EF-hand domain containing 1	EWS RNA binding protein 1
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cajal Body Membrane
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Regulation Of DNA-templated Transcription
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases			Extraskeletal myxoid chondrosarcoma Myxoid liposarcoma Ewing's sarcoma Clear cell sarcoma of soft tissue
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Hypoalbuminemia ( 34050200) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)	Breast cancer ( 23535729) Pancreatic cancer ( 25086665) Platelet count ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 CALCOCO2 CEP55 CFAP68 CTAG1A CTAG1B DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG UBC USP9X VPS37C WWOX ZIC1	164 interacting genes: ACTL6A AGT ANXA11 ARID1A ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BRME1 BTK C11orf16 CALM1 CCDC7 CCDC91 CD177 CDK12 CEACAM5 CEBPA CETP CFAP298 CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EPAS1 ERCC5 FAM131C FASN FLI1 FXR2 GNPDA1 GPBP1L1 H2BC15 HBP1 HDAC3 HERPUD1 HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 OGT PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B PTP4A2 RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SELENOI SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SMARCC1 SMARCC2 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		553115	2130
HPRD ID		10143	00592
Ensembl ID		ENSG00000162517	ENSG00000182944
Uniprot IDs		A0A384MQX5 Q9UBV8	A0A0D9SFL3 Q01844
PDB IDs		8RBH	2CPE
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Exit Site COPII Vesicle Coat Protein Binding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport	Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Nucleus Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-templated Transcription Transcription Regulator Complex Chromatin Remodeling MRNA Metabolic Process Brahma Complex NpBAF Complex RNA Metabolic Process Regulation Of Gene Expression Nucleic Acid Binding Chromatin Single-stranded DNA Binding Protein-containing Complex Negative Regulation Of DNA-templated Transcription Cardiac Conduction System Development Chromatin Binding Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Protein Binding MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Nucleosome Disassembly TORC1 Signaling Negative Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?