PEF1 and ANKRD10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PEF1	ANKRD10
Description		penta-EF-hand domain containing 1	ankyrin repeat domain 10
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Nucleoplasm
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Hypoalbuminemia ( 34050200) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)	Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Refractive error ( 32231278)
Interacting Genes		40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 CALCOCO2 CEP55 CFAP68 CTAG1A CTAG1B DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG UBC USP9X VPS37C WWOX ZIC1	16 interacting genes: APPBP2 ATG9A CSTF2 FAM222B FOXI1 GIGYF1 OTX1 PEF1 PITX1 POGZ POU6F2 SHC3 SNRPC TLX3 TRIP13 ZIC1
Entrez ID		553115	55608
HPRD ID		10143	12455
Ensembl ID		ENSG00000162517	ENSG00000088448
Uniprot IDs		A0A384MQX5 Q9UBV8	Q9NXR5
PDB IDs		8RBH
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Exit Site COPII Vesicle Coat Protein Binding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport	DNA-binding Transcription Factor Activity Inner Ear Morphogenesis Central Nervous System Development Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Embryonic Morphogenesis
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