PSPC1 and WBP4

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		PSPC1	WBP4
Gene Name		paraspeckle component 1	WW domain binding protein 4
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck
	Molecular Function	Nucleotide Binding Core Promoter Binding Protein Binding Poly(A) RNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	Transcription, DNA-templated Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process	MRNA Cis Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		7 interactors: KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4	44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		55269	11193
HPRD ID		10172	16086
Ensembl ID			ENSG00000120688
Uniprot IDs		B4DWI8 Q8WXF1	B7Z4M2 O75554
PDB IDs		3SDE	2DK1 2JXW
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing Regulation Of Cellular Response To Oxidative Stress MRNA Processing MRNA Metabolic Process Regulation Of Circadian Rhythm RNA Metabolic Process RNA Processing Gene Expression Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing, Via Transesterification Reactions DNA Recombination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Cellular Nitrogen Compound Metabolic Process Rhythmic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Circadian Rhythm Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Cell Death Histone H3 Deacetylation DNA Repair Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Histone Deacetylation Cellular Response To DNA Damage Stimulus Protein Deacetylation Biosynthetic Process	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress
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