PSPC1 and TCERG1

Number of citations of the paper that reports this interaction (PubMedID 16055720)
76

Data Source:
BioGRID (pull down)

		PSPC1	TCERG1
Description		paraspeckle component 1	transcription elongation regulator 1
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Transcription Elongation Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase Binding
	Biological Process	Activation Of Innate Immune Response Immune System Process Regulation Of DNA-templated Transcription Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of DNA-templated Transcription Rhythmic Process Membraneless Organelle Assembly	Negative Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		16 interacting genes: CEBPA DANCR DISC1 ESR1 KRT31 KRTAP13-1 LRIF1 LZTS1 NEIL3 NONO NUDT21 SFPQ TCERG1 WBP4 ZRANB1 ZSCAN5B	56 interacting genes: ABI1 AURKA BARD1 CEBPA CHAF1A CHD3 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 RNF10 RUNX1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO2 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		55269	10915
HPRD ID		10172	10393
Ensembl ID		ENSG00000121390	ENSG00000113649
Uniprot IDs		Q8WXF1	A0A7P0T8N8 O14776
PDB IDs		3SDE 5IFN 5WPA	2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG 7ABF 7ABG 8Q7N 8QO9
Enriched GO Terms of Interacting Partners?		Paraspeckles Nuclear Matrix MRNA Processing Chromatin Binding Histone Deacetylase Binding RNA Metabolic Process RNA Polymerase II Transcription Regulator Complex Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nuclear Speck Nucleoplasm RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding RNA Processing Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Pro-B Cell Differentiation MCM Complex Binding Nucleobase-containing Compound Metabolic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex RNA Splicing MRNA Processing MRNA Metabolic Process RNA Binding Catalytic Step 2 Spliceosome Spliceosomal Complex Assembly Nucleic Acid Metabolic Process Nuclear Speck Nucleoplasm U2-type Prespliceosome Assembly Nucleus Nucleic Acid Binding U2 SnRNP RNA Metabolic Process Nucleobase-containing Compound Metabolic Process U2-type Spliceosomal Complex U2-type Precatalytic Spliceosome RNA Processing Protein-containing Complex Assembly Protein-containing Complex Organization Protein-RNA Complex Assembly Paraspeckles Cellular Component Assembly MRNA Splice Site Recognition MRNA 3'-splice Site Recognition U2-type Prespliceosome Regulation Of RNA Splicing SCAR Complex Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Nuclear Matrix Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Actin Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Actin Polymerization Or Depolymerization Alternative MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex MRNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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