PSPC1 and SFPQ

Number of citations of the paper that reports this interaction (PMID 15140795)
9

Data Source:
HPRD (in vivo)

		PSPC1	SFPQ
Gene Name		paraspeckle component 1	splicing factor proline/glutamine-rich
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Paraspeckles
	Molecular Function	Nucleotide Binding Core Promoter Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Transcription Regulatory Region Sequence-specific DNA Binding Core Promoter Binding Protein Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Alternative MRNA Splicing, Via Spliceosome DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Histone H3 Deacetylation Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Endometrial cancer ( 21499250)
Protein-Protein Interactions		7 interactors: KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4	27 interactors: APBB1 AR CSNK2A1 ERG EXOSC5 FHL2 FUS GAS7 HIST3H3 HN1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC WBP4 ZMYM2
Entrez ID		55269	6421
HPRD ID		10172	07284
Ensembl ID			ENSG00000116560
Uniprot IDs		B4DWI8 Q8WXF1	P23246 Q86VG2
PDB IDs		3SDE
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing Regulation Of Cellular Response To Oxidative Stress MRNA Processing MRNA Metabolic Process Regulation Of Circadian Rhythm RNA Metabolic Process RNA Processing Gene Expression Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing, Via Transesterification Reactions DNA Recombination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Cellular Nitrogen Compound Metabolic Process Rhythmic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Circadian Rhythm Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Cell Death Histone H3 Deacetylation DNA Repair Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Histone Deacetylation Cellular Response To DNA Damage Stimulus Protein Deacetylation Biosynthetic Process	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of Circadian Rhythm RNA Splicing MRNA Metabolic Process Transcription, DNA-templated MRNA Processing RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Apoptotic Process RNA Processing Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Circadian Rhythm Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Cycle Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Biosynthetic Process
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