PSPC1 and NONO

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vivo, in vitro)

		PSPC1	NONO
Gene Name		paraspeckle component 1	non-POU domain containing, octamer-binding
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Nucleus Nucleoplasm Nucleolus Membrane Nuclear Matrix Nuclear Speck Paraspeckles
	Molecular Function	Nucleotide Binding Core Promoter Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Core Promoter Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process	DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4	35 interactors: APBB1 AR C11orf68 CA2 DDX6 ERG EWSR1 FXR2 HIST3H3 IL7R IRAK3 LMO4 MAD1L1 NUPR1 ORC5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 WBP4 YLPM1 ZNRD1
Entrez ID		55269	4841
HPRD ID		10172	02098
Ensembl ID			ENSG00000147140
Uniprot IDs		B4DWI8 Q8WXF1	Q15233
PDB IDs		3SDE	3SDE
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing Regulation Of Cellular Response To Oxidative Stress MRNA Processing MRNA Metabolic Process Regulation Of Circadian Rhythm RNA Metabolic Process RNA Processing Gene Expression Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Splicing, Via Transesterification Reactions DNA Recombination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Cellular Nitrogen Compound Metabolic Process Rhythmic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Circadian Rhythm Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Cell Death Histone H3 Deacetylation DNA Repair Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Histone Deacetylation Cellular Response To DNA Damage Stimulus Protein Deacetylation Biosynthetic Process	Regulation Of Gene Expression RNA Metabolic Process Gene Expression Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Nucleosome Disassembly Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Triglyceride Catabolic Process Rhythmic Process Photoperiodism Entrainment Of Circadian Clock Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Acylglycerol Catabolic Process Cell Cycle Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Chromatin Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Glycogen Catabolic Process Energy Reserve Metabolic Process Chromatin Organization Chromosome Organization Biosynthetic Process Regulation Of Cellular Process Glycogen Metabolic Process MRNA Metabolic Process RNA Splicing Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Cellular Component Organization Polysaccharide Metabolic Process
Tagcloud ?			acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2
Tagcloud (Difference) ?			acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2
Tagcloud (Intersection) ?