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DUS2 and TK1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
DUS2
TK1
Gene Name
dihydrouridine synthase 2
thymidine kinase 1, soluble
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Cytosol
Molecular Function
Double-stranded RNA Binding
Protein Kinase Inhibitor Activity
Protein Binding
TRNA Dihydrouridine Synthase Activity
Flavin Adenine Dinucleotide Binding
Thymidine Kinase Activity
ATP Binding
Zinc Ion Binding
Nucleoside Kinase Activity
Identical Protein Binding
Biological Process
TRNA Dihydrouridine Synthesis
Negative Regulation Of Protein Kinase Activity
Oxidation-reduction Process
Negative Regulation Of Cell Death
Liver Development
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Nucleotide Biosynthetic Process
Response To Toxic Substance
Skeletal Muscle Cell Proliferation
Phosphorylation
Response To Nutrient Levels
Pyrimidine Nucleoside Salvage
Small Molecule Metabolic Process
Thymidine Metabolic Process
Response To Copper Ion
Digestive Tract Development
Protein Homotetramerization
Response To Cortisol
Nucleobase-containing Small Molecule Metabolic Process
Fetal Process Involved In Parturition
DNA Biosynthetic Process
Pathways
Pyrimidine salvage reactions
Pyrimidine metabolism
Metabolism of nucleotides
Drugs
Dithioerythritol
Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
EPRS
PVRL2
SMN1
TK1
159 interactors:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ASNA1
ATG16L2
ATP5B
ATP6V1A
ATXN3
BAG6
C14orf1
C19orf60
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CPSF3L
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
EEF1A1
EIF3G
EIF4A2
EIF6
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
FZR1
GAPDH
GDF9
GDI1
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LOC148413
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS
RBBP4
RBM48
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPT6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO3
TAF1C
TCTEX1D2
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR60
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
54920
7083
HPRD ID
08624
01771
Ensembl ID
ENSG00000167264
ENSG00000167900
Uniprot IDs
B4DKP8
E7EUN9
Q9NX74
P04183
PDB IDs
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Coreceptor-mediated Virion Attachment To Host Cell
Fetal Process Involved In Parturition
Prolyl-tRNA Aminoacylation
Susceptibility To T Cell Mediated Cytotoxicity
Sperm Mitochondrion Organization
Skeletal Muscle Cell Proliferation
Fusion Of Virus Membrane With Host Plasma Membrane
Glutamyl-tRNA Aminoacylation
Susceptibility To Natural Killer Cell Mediated Cytotoxicity
Thymidine Metabolic Process
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Response To Cortisol
Virion Attachment To Host Cell
Deoxyribonucleoside Monophosphate Biosynthetic Process
Positive Regulation Of Immune Response To Tumor Cell
Adhesion Of Symbiont To Host
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
NcRNA Metabolic Process
Positive Regulation Of Mast Cell Activation
Acrosome Assembly
Establishment Of Mitochondrion Localization
Parturition
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Response To Copper Ion
Regulation Of Natural Killer Cell Mediated Immunity
Spermatid Nucleus Differentiation
Positive Regulation Of Immunoglobulin Mediated Immune Response
Regulation Of Mast Cell Activation
Mitochondrion Localization
Pyrimidine Nucleobase Metabolic Process
Secretory Granule Organization
Multicellular Organismal Reproductive Process
Viral Entry Into Host Cell
Spliceosomal SnRNP Assembly
Multicellular Organism Reproduction
Entry Into Host Cell
Pyrimidine Nucleoside Biosynthetic Process
Spliceosomal Complex Assembly
Protein Complex Assembly
Reproduction
Protein Homotetramerization
Pyrimidine Nucleoside Metabolic Process
Single Organism Reproductive Process
Positive Regulation Of T Cell Mediated Cytotoxicity
Negative Regulation Of Translation
Adherens Junction Organization
Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Protein Metabolic Process
Developmental Process
Anatomical Structure Development
System Development
Regulation Of Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Localization
Metabolic Process
Regulation Of Metabolic Process
Organelle Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Protein Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Catabolic Process
RNA Metabolic Process
Negative Regulation Of Cell Cycle
Posttranscriptional Regulation Of Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Cell Differentiation
Platelet Degranulation
Gene Expression
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Mitotic Cell Cycle
Cellular Process
Biosynthetic Process
Regulation Of Cell Cycle
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cycle Process
Mitotic Cell Cycle Process
Axon Guidance
Chromatin Organization
Viral Process
Programmed Cell Death
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Chromosome Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Organic Substance
Mitotic Cell Cycle
Cellular Response To Growth Factor Stimulus
Tagcloud
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Difference)
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Intersection)
?