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PRKAG3 and PRKAB2
Number of citations of the paper that reports this interaction (PMID
10698692
)
99
Data Source:
BioGRID
(two hybrid)
PRKAG3
PRKAB2
Gene Name
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
protein kinase, AMP-activated, beta 2 non-catalytic subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytosol
AMP-activated Protein Kinase Complex
Nucleoplasm
Cytosol
AMP-activated Protein Kinase Complex
Molecular Function
AMP-activated Protein Kinase Activity
ATP Binding
Protein Kinase Binding
AMP-activated Protein Kinase Activity
Protein Binding
Identical Protein Binding
Biological Process
Glycogen Biosynthetic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Insulin Receptor Signaling Pathway
Glucose Transport
Intracellular Signal Transduction
Membrane Organization
Energy Reserve Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Fatty Acid Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Protein Kinase Activity
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-mediated signalling
Regulation of Rheb GTPase activity by AMPK
mTOR signalling
Translocation of GLUT4 to the plasma membrane
IRS-related events
mTOR signalling
IGF1R signaling cascade
Mitochondrial biogenesis
IRS-related events triggered by IGF1R
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Drugs
Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
BRCA1
CRYAB
LMCD1
NGRN
PRKAA1
PRKAB1
PRKAB2
70 interactors:
ADAMTSL4
BANP
BEND5
BLZF1
CALCOCO2
CASP6
CCDC33
CCDC36
CDX4
CREB3L1
CRX
CSNK2B
DAO
DDIT4L
DICER1
DST
EPM2A
FAM208B
FDX1
FLNC
GATA1
GATAD2B
GET4
GNB2L1
GOLGA2
GRN
IKZF1
IKZF3
KCTD5
KLF15
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LZTS2
MAGED1
MDFI
MEOX2
NEBL
PIAS2
PRDM14
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
PSME3
PYGM
RBPMS
REL
RHEBL1
RIMBP3
SPRY2
STX11
STX19
TADA2A
TCF4
TP53BP2
TRAF2
TRIM10
UBXN11
YY1AP1
ZBTB32
Entrez ID
53632
5565
HPRD ID
16085
04117
Ensembl ID
ENSG00000115592
ENSG00000131791
Uniprot IDs
B4DUK8
Q9UGI9
O43741
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2Y94
2YA3
4EAI
4EAJ
Enriched GO Terms of Interacting Partners
?
Fatty Acid Biosynthetic Process
Fatty Acid Metabolic Process
Response To Hormone
Negative Regulation Of Cell Cycle
Cellular Response To Organonitrogen Compound
Regulation Of Lipid Biosynthetic Process
Response To Ionizing Radiation
Cell Cycle Arrest
Insulin Receptor Signaling Pathway
Lipid Biosynthetic Process
Monocarboxylic Acid Metabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Fatty Acid Biosynthetic Process
Response To Organonitrogen Compound
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Response To Insulin
Regulation Of Lipid Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Lipid Biosynthetic Process
Regulation Of Cell Cycle
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Cellular Lipid Metabolic Process
Response To Gamma Radiation
Carboxylic Acid Metabolic Process
Cell Cycle Process
Regulation Of Protein Metabolic Process
Organic Acid Metabolic Process
Protein Oligomerization
Response To Radiation
Negative Regulation Of Lipid Metabolic Process
Response To Peptide Hormone
Response To Organic Substance
Lipid Metabolic Process
Regulation Of Fatty Acid Metabolic Process
Response To Peptide
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Negative Regulation Of Glucosylceramide Biosynthetic Process
Cold Acclimation
Cell Cycle
Cellular Response To Hormone Stimulus
Response To Hydrogen Peroxide
Positive Regulation Of Histone H3-K9 Acetylation
Protein Heterooligomerization
Organelle Organization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Arrest
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Glycolytic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Polysaccharide Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Organelle Organization
Gene Expression
Cell Cycle Process
Positive Regulation Of Phosphorylation
RNA Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Fatty Acid Biosynthetic Process
Cellular Process
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Binding
Regulation Of Metabolic Process
Regulation Of Carbohydrate Metabolic Process
Regulation Of Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Death
Tagcloud
?
accompanying
adjust
alga0035896
asga0009814
asga0070634
beadchip
bonferroni
color
consumers
corresponds
deregressed
finnish
ham
illumina
lightness
loin
meat
megabases
polygenic
porcinesnp60
qlt
rcn1
redness
relatedness
smallest
snp
substitutions
traits
yorkshire
Tagcloud (Difference)
?
accompanying
adjust
alga0035896
asga0009814
asga0070634
beadchip
bonferroni
color
consumers
corresponds
deregressed
finnish
ham
illumina
lightness
loin
meat
megabases
polygenic
porcinesnp60
qlt
rcn1
redness
relatedness
smallest
snp
substitutions
traits
yorkshire
Tagcloud (Intersection)
?