HOOK1 and AKTIP

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vivo)

		HOOK1	AKTIP
Gene Name		hook microtubule-tethering protein 1	AKT interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Nucleolus Cytoplasm Golgi Apparatus Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Positive Regulation Of Protein Phosphorylation Apoptotic Process Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Ubiquitination Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	23 interactors: AKT1 ASS1 C10orf2 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT KIAA1377 MARCH5 PDPK1 POLA2 RPA1 TRIM23 TRIM41 UTP14A VPS16 VPS18 VPS41
Entrez ID		51361	64400
HPRD ID		07428	07467
Ensembl ID		ENSG00000134709	ENSG00000166971
Uniprot IDs		Q9UJC3	Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Protein Localization Organelle Organization Endosomal Transport Endomembrane System Organization Cytoplasmic Transport Cellular Localization Intracellular Transport Establishment Of Localization In Cell Regulation Of Vesicle Fusion Protein Localization To Organelle DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Protein Ubiquitination Cellular Protein Localization Nuclear DNA Replication Telomere Maintenance Via Recombination Protein Modification By Small Protein Conjugation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Epidermal Growth Factor Stimulus Vesicle-mediated Transport Positive Regulation Of Protein Localization To Plasma Membrane Response To Epidermal Growth Factor Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Protein Import Into Nucleus, Translocation Regulation Of Vesicle-mediated Transport DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening G1/S Transition Of Mitotic Cell Cycle Response To Fluid Shear Stress Cytoplasmic Microtubule Organization Viral Entry Into Host Cell Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Temperature Stimulus Viral Life Cycle Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Argininosuccinate Metabolic Process Regulation Of Vacuole Fusion, Non-autophagic
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Intersection) ?