HOOK1 and VPS18

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		HOOK1	VPS18
Gene Name		hook microtubule-tethering protein 1	vacuolar protein sorting 18 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Actin Filament HOPS Complex Late Endosome Membrane
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Actin Binding Protein Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Lysosome Organization Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	18 interactors: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		51361	57617
HPRD ID		07428	09776
Ensembl ID		ENSG00000134709	ENSG00000104142
Uniprot IDs		Q9UJC3	Q9P253
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Establishment Of Localization In Cell Intracellular Protein Transport Cellular Localization Vesicle Fusion Cellular Protein Localization Transport Organelle Fusion Vesicle Organization Membrane Fusion Vesicle Docking Endosomal Transport Early Endosome To Late Endosome Transport Membrane Docking Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Vesicle Docking Involved In Exocytosis Membrane Organization Vacuolar Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Organelle Organization Organelle Localization Viral Entry Into Host Cell Entry Into Host Cell Vesicle Localization Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Protein Localization To Plasma Membrane Histone H2B Acetylation Regulation Of Vacuole Fusion, Non-autophagic Positive Regulation Of Receptor Localization To Synapse Regulation Of DNA-templated Transcription In Response To Stress Lysosome Organization Positive Regulation Of Protein Binding Exocytosis N-terminal Peptidyl-lysine Acetylation Regulation Of Protein Localization Cellular Response To Hypoxia Regulation Of Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Interaction With Host Vacuole Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Oxygen Levels Regulation Of Tubulin Deacetylation
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated
Tagcloud (Intersection) ?