HOOK1 and VPS41

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
HPRD (in vivo)

		HOOK1	VPS41
Gene Name		hook microtubule-tethering protein 1	vacuolar protein sorting 41 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Lysosomal Membrane Early Endosome Late Endosome Golgi-associated Vesicle Cytosol Microtubule Cytoskeleton Membrane HOPS Complex CORVET Complex
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Molecular_function Protein Binding Microtubule Binding Zinc Ion Binding GTPase Binding
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Protein Targeting To Vacuole Biological_process Vesicle-mediated Transport Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Golgi Vesicle Transport
Pathways
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	9 interactors: AKTIP AP3D1 APP HOOK1 HOOK2 HOOK3 MON1B UBE2U ZNF512B
Entrez ID		51361	27072
HPRD ID		07428	10402
Ensembl ID		ENSG00000134709	ENSG00000006715
Uniprot IDs		Q9UJC3	E9PF36 P49754
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Early Endosome To Late Endosome Transport Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Lysosome Organization Endosomal Transport Vacuolar Transport Vacuole Organization Vesicle-mediated Transport Endomembrane System Organization Cytoplasmic Transport Intracellular Transport Establishment Of Localization In Cell Cellular Localization Protein Transport Establishment Of Protein Localization Axon Cargo Transport Organelle Organization Protein Localization Transport Synaptic Growth At Neuromuscular Junction Synaptic Vesicle Membrane Organization Microtubule-based Transport Collateral Sprouting In Absence Of Injury Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Binding Eye Pigment Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Microtubule-based Process Axon Choice Point Recognition Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Pigment Granule Maturation Endosome To Melanosome Transport Neuron Remodeling Cellular Pigment Accumulation Regulation Of Binding Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Neurogenesis Protein Localization To Centrosome Golgi Localization Microtubule-based Movement Negative Regulation Of Cell Development Cellular Copper Ion Homeostasis Interkinetic Nuclear Migration
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated
Tagcloud (Intersection) ?