HOOK1 and ANKRD23

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOOK1	ANKRD23
Description		hook microtubule tethering protein 1	ankyrin repeat domain 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton HOPS Complex FHF Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Intercalated Disc Actin Cytoskeleton Myofibril I Band
	Molecular Function	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding	Transcription Cis-regulatory Region Binding Protein Binding Titin Binding
	Biological Process	Golgi Organization Endosome Organization Lysosome Organization Spermatogenesis Spermatid Development Endosome To Lysosome Transport Protein Transport Cell Differentiation Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly Protein Localization To Perinuclear Region Of Cytoplasm	Fatty Acid Metabolic Process Response To Mechanical Stimulus Response To Muscle Stretch Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Sarcomere Organization
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Bipolar disorder ( 31043756)
Interacting Genes		46 interacting genes: AKTIP ANK3 ANKRD23 AP1M1 AP4M1 CCDC9 CDC5L CDK4 CUL1 CWF19L2 DENND1B ESS2 EXOSC7 FAM161A FHIP1B HNRNPLL HOOK2 HOOK3 KAT5 LENG1 LMO2 MEOX2 PIAS2 PRPF6 RBM22 RNF10 RPS7 SNW1 TBC1D7 TFIP11 UNKL USP2 UTP14A UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80	20 interacting genes: CCDC102B CCDC57 CDCA7L CLIC3 ENKD1 FAM90A1 GRB2 HOOK1 HRAS IQUB KDM1A KIFC3 MIPOL1 MYPN NAP1L1 PIBF1 POLR3C SMARCD1 TRIM41 TTN
Entrez ID		51361	200539
HPRD ID		07428	12462
Ensembl ID		ENSG00000134709	ENSG00000163126
Uniprot IDs		Q9UJC3	Q86SG2
PDB IDs
Enriched GO Terms of Interacting Partners?		HOPS Complex Endosome To Lysosome Transport Vacuolar Transport Lysosomal Transport FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Lysosome Organization Vacuole Organization Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Catalytic Step 2 Spliceosome Vesicle Organization Early Endosome To Late Endosome Transport MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Clathrin-coated Vesicle AP-3 Adaptor Complex Endosome Organization RNA Processing Regulation Of Transcription By RNA Polymerase II Lysosomal HOPS Complex Protein Transport Endosomal Transport Spliceosomal Complex MRNA Processing Establishment Of Protein Localization MRNA Metabolic Process Zinc Ion Binding RNA Splicing U2-type Catalytic Step 2 Spliceosome Vesicle-mediated Transport Nucleus Intracellular Transport Regulation Of Macromolecule Metabolic Process RNA Metabolic Process CORVET Complex Regulation Of Gene Expression Vesicle Fusion Regulation Of Metabolic Process Nuclear Speck Organelle Membrane Fusion Regulation Of DNA-templated Transcription Positive Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Localization Regulation Of Primary Metabolic Process Nucleic Acid Metabolic Process Protein Targeting To Vacuole Clathrin Adaptor Complex	Cytoskeleton Organization Centrosome Cellular Response To Ionizing Radiation Schwann Cell Development Microtubule-based Process Muscle Alpha-actinin Binding Cilium Assembly Positive Regulation Of Multicellular Organismal Process Cilium Organization I Band Cellular Response To Gamma Radiation Response To Ionizing Radiation Plasma Membrane Bounded Cell Projection Assembly
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